Balachandran W. – TechConnect Briefs

DNA Extraction, Purification and Quantification Using Micromachined Microfluidic Chip

Azimi S.M., Nixon G., Ahern J., Balachandran W., Brunel University, UK

This paper introduces a new DNA extraction and purification method from whole blood. Mixing and separation steps are performed using functionalised superparamagnetic beads suspended in cell lysis buffer in a circular chamber that is sandwiched [...]

Modelling of Low Level Ionic Current Sensing Micro-tip

Memon S., Balachandran W., Brunel Univeristy, West London, UK

The authors of this paper are developing an appropriate micro/nano array sensors that is capable of sensing ionic currents in sweat fluid secreted from sweat pores on the finger ridges. In this paper we present [...]

DNA Extraction Chip Using Key-type Planar Electrodes

Azimi S.M., Balachandran W., Ahern J., Slijepcevic P., Newton C., Brunel University, UK

This paper presents a novel method of DNA extraction from whole blood using time varying magnetic field. The novelty of this chip is that both mixing and separation steps are performed in a single chamber [...]

A Microfluidic Mixer for Chaotic Mixing of Magnetic Particles

Zolgharni M., Azimi S.M., Bahmanyar M.R., Balachandran W., Brunel University, UK

Magnetic isolation of specific biological entities through utilizing super-paramagnetic micro-particles has been of great interest in both bench-top and microfluidic platforms. Since the magnetic particles and target entities are suspended in separate fluids, prior to [...]

Using Spiral Inductors for Detecting Hybridization of DNAs Labeled with Magnetic Beads

Azimi S.M., Bahmanyar M.R., Zolgharni M., Balachandran W., Brunel University, UK

This paper introduces an inductance-based sensor for detection of DNA hybridization and investigates its performance by means of computer simulation. In order to detect the occurrence of hybridization, single strand target DNA’s are tagged with [...]