magnetic bead – TechConnect Briefs

DNA Extraction, Purification and Quantification Using Micromachined Microfluidic Chip

Azimi S.M., Nixon G., Ahern J., Balachandran W., Brunel University, UK

This paper introduces a new DNA extraction and purification method from whole blood. Mixing and separation steps are performed using functionalised superparamagnetic beads suspended in cell lysis buffer in a circular chamber that is sandwiched [...]

Amperometric Detection of Staphylococcal Enterotoxin B in milk using Magnetic Bead-Based Immunoassay on Disposable Screen Printed Carbon Electrode Strip

Rastogi S.K., Gibbon S., Branen A.L., Branen J.R., Branen A.L., Branen J.R., University of Idaho, US

A novel approach for the sensitive detection of Staphylococcal enterotoxin B (SEB) in milk is reported. The method used sandwich enzyme-linked immunoassay with SEB specific antibodies on magnetic beads. A small cylindrical magnet was fixed, [...]

DNA Extraction Chip Using Key-type Planar Electrodes

Azimi S.M., Balachandran W., Ahern J., Slijepcevic P., Newton C., Brunel University, UK

This paper presents a novel method of DNA extraction from whole blood using time varying magnetic field. The novelty of this chip is that both mixing and separation steps are performed in a single chamber [...]

Using Spiral Inductors for Detecting Hybridization of DNAs Labeled with Magnetic Beads

Azimi S.M., Bahmanyar M.R., Zolgharni M., Balachandran W., Brunel University, UK

This paper introduces an inductance-based sensor for detection of DNA hybridization and investigates its performance by means of computer simulation. In order to detect the occurrence of hybridization, single strand target DNA’s are tagged with [...]