hybridization – TechConnect Briefs

Highly Tunable Surface Plasmons Resonance Using Metal/metal Oxide Hybrid Nanostructures

Khosroabadi A.A., Gangopadhyay P., Norwood R.A., University of Arizona, US

Metal and metal oxide electrodes play a significant role in many cutting edge applications including photonics, membranes, biological supports, sensing, electrochromics, and in various green technologies, such as, photocatalytics, Li-ion batteries and photovoltaics. There is [...]

Different contribution of carbon nanotubes and graphene oxide in single nucleotide polymorphism for the diagnosis of human mad-cow disease

Choi W., Lee J-H., Luminescent MD, LLC, US

Rapid single nucleotide polymorphism (SNP) with 1,1’-oxalylimidazole chemiluminescence (ODI-CL) detection was developed for the early diagnosis of human mad-cow disease. Mutated single strand DNA (ssDNA) sequence discovered from patients having human mad-cow disease rapidly hybridize [...]

Mathematical modeling and computer simulation of Brownian motion and hybridization of nanoparticle-bioprobe-polymer complexes in the low concentration limit

Toth A., Banky D., Grolmusz V., Eotvos University, HU

We present a mathematical model and the computer simulation of Brownian motion of nanoparticle-bioprobe-polymer contrast agent complexes and their hybridization to immobilized targets. Our model is a stochastic counterpart of the continuous model presented in [...]

Carbon Nanotube Interfaces for Single Molecular Level Bio Sensing

Choi W.B., Vedala H., Roy S., Kim T-H., Florida International University, US

Single molecule detection, aimed both at fundamental investigation and applications, has recently been attracting a lot of attentions. The present set of studies is focused on the design, fabrication and optimization of novel carbon nanotube(CNT) [...]

Quantum dot (Qdot) labeling of gene expression analysis and single molecule imaging in neurons

Jeromin A., Riley Z., Byrnes E., Parry S., Smith S., Dee N., Jones A., Allen Institute for Brain Science, US

The Allen Brain Atlas1 is the first large scale atlas of gene expression in the mouse brain, using chromogenic in situ hybridization (cISH) of over 20,000 genes.Qdots have excellent potential for muliplex imaging of gene [...]

Carbon Nanotube Interfaces for Single Molecular Level Bio Sensing

Choi W.B., Vedala H., Roy S., Kim T-H., Florida International University, US

Single molecule detection, aimed both at fundamental investigation and applications, has recently been attracting a lot of attentions. The present set of studies is focused on the design, fabrication and optimization of novel carbon nanotube(CNT) [...]

Hybridization of CMOS with CNT-based Complementary Nano Electro-Mechanical Switch for Low-Leakage and Robust Embedded Memory Design

Chakraborty R.S., Narasimhan S., Bhunia S., Case Western Reserve University, US

Embedded static random access memory (SRAM) that constitutes an integral part of nanoelectronic systems, experiences two major challenges with aggressive technology scaling: 1) exponential increase in leakage current [1] and 2) decrease in robustness of [...]

Enhancement of DNA Microarray Hybridization using Shear-Driven Microfluidics

Vanderhoeven J., Pappaert K., Dutta B., Vanhummelen P., Baron G.V., Desmet G., Free University of Brussels, BE

On microarrays the transport of the target molecules towards the spots only occurs by molecular diffusion. As a result, microarray analyses require overnight incubation and are highly inefficient in terms of capture rate and detection [...]