Case Western Reserve University – TechConnect Briefs

Novel Nanoeletromechanical Switches for VLSI Power Integrity Improvement

Zhang R., Saab D., Masoo M., Case Western Reserve University, US

Complementary Metal Oxide Semiconductor(CMOS)is facing extreme difficulties to realize energy efficient designs while the scaling of channel length has been being at the same pace in the past several decades.In this paper,we presented a novel [...]

β3 Integrin siRNA-Loaded Multifunctional Nanoparticle Therapy for Metastatic Breast Cancer

Gujrati M., Parvani J.G., Schiemann W.P., Lu Z.R., Case Western Reserve University, US

Successful siRNA-mediated cancer therapy requires the use of multifunctional nanoparticle systems to overcome the barriers associated with delivery. We have recently developed a cationic lipid-based carrier, ECO, which efficiently delivers siRNA intracellularly to induce potent [...]

Development and Application of a Rod and Sphere-Shaped Viral Nanoparticle MRI Contrast Agent for Atherosclerosis Diagnosis

Bruckman M.A., Steinmetz N.F., Case Western Reserve University, US

The use of nanoparticles to deliver magnetic resonance (MR) contrast agents to enhance MR sensitivity has shown great potential in identifying and diagnosing diseases such as cancer and cardiovascular disease. A common challenge is the [...]

Hybridization of CMOS with CNT-based Complementary Nano Electro-Mechanical Switch for Low-Leakage and Robust Embedded Memory Design

Chakraborty R.S., Narasimhan S., Bhunia S., Case Western Reserve University, US

Embedded static random access memory (SRAM) that constitutes an integral part of nanoelectronic systems, experiences two major challenges with aggressive technology scaling: 1) exponential increase in leakage current [1] and 2) decrease in robustness of [...]

Self-Welded Metal-Catalyzed Carbon Nanotube Piezoresistors with Very Large Longitudinal Piezoresistivity of ~ 4×10-8 Pa-1

Tabib-Azar M., Wang R., Xie Y., Case Western Reserve University, US

Self-welded multi-walled carbon nanotube (MWCNT) bridges, grown using low-pressure metal-catalyzed chemical vapor deposition technique between silicon posts, were used as tiny piezoresistors to monitor vibration and bending/deformation of silicon cantilever beams for the first time. [...]

Numerical Fracture Analysis of MEMS Devices

Tayebi A.K., Tayebi N., Tayebi A.K., Tayebi N., Case Western Reserve University, US

Non-conventional finite element analysis (FEA) based on linear elastic fracture mechanics (LEFM) is applied to fractured MEMS specimens with notches. The objective of this paper is to test the applicability of LEFM at mesoscale and [...]