Vanderhoeven J., Pappaert K., Dutta B., Vanhummelen P., Baron G.V., Desmet G.
Free University of Brussels, BE
Keywords: hybridization, microarray, microfluidics, shear-driven
On microarrays the transport of the target molecules towards the spots only occurs by molecular diffusion. As a result, microarray analyses require overnight incubation and are highly inefficient in terms of capture rate and detection limit. To overcome this diffusion limitation, several solutions have already been proposed: electrokinetic flows, ultra-sound mixing, pump-around systems, etc…. The present study demonstrates how DNA microarray analysis is enhanced by miniaturization. Only a small sample volume (
Journal: TechConnect Briefs
Volume: 1, Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 1
Published: May 8, 2005
Pages: 343 - 346
Industry sector: Medical & Biotech
Topic: Biomaterials
ISBN: 0-9767985-0-6