genotoxicity – TechConnect Briefs

Evaluation of the genotoxic potential of different types of nanofibrillated celluloses

Catalán J., Lindberg H.K., Aimonen K.J., Wolff H., Wedin I., Nuopponen M., Savolainen K.M., Norppa H., Finnish Institute of Occupational Health, FI

Nanofibrillar cellulose (NFC) is among the most promising innovations in the forest industry. Due to its unique properties, NFC has a wide variety of possible applica-tions. As NFC consists of thin and long fibres with [...]

Quantitative Assessment of Nanoparticle Induced Oxidative DNA Damage Using Isotope Dilution Mass Spectrometry

Petersen E.J., Marquis B.J., Jaruga P., Dizdaroglu M., Nelson B.C., National Institute of Standards and Technology, US

Hyphenated mass spectrometry (gas chromatography/mass spectrometry) techniques have been employed as one of the primary analytical tools for investigating the effects of ionizing radiation, chemical/biological carcinogens and oxygen derived free radicals on the induction and [...]

Cytotoxicity and genotoxicity of silver nanomaterials

Uyguy B., Mason M.D., Ng A-K., University of Southern Maine, US

Summary We have investigated the cytotoxic effect of dialyzed silver nanoparticles (Ag NPs), PEGylated Ag NPs and silver nanorods on human cultured cells. The cytotoxicity of 24 h treatment with Ag NPs at 0.25, 0.5, [...]