gene expression – TechConnect Briefs

Impact of Docetaxel conjugated Nanodiamonds on Gene expression of Prostate Cancer (PC3) Cells

Cedeño Ortiz J.D., Joshi S., Singh S.R., Vig K., Alabama State University, US

Prostate cancer (PC) is the second leading cause of adult male death in the United States. This type of cancer is a disease where the prostate gland cells start to grow without control, changing in [...]

miRNA Expression Analysis in HEp-2 Cells after Gold Nanorod Application

Montgomery A., Bawage S., Chaudhary A., Singh S.R., Vig K., Alabama State University, US

Gold Nanoparticles are popular because of their use in drug delivery and other biomedical applications. However, not much is known about their toxicity. The purpose of the present study was to evaluate the toxicity of [...]

Efficiency of different chitosan and its derivative nanoparticles for delivery of recombinant plasmid of Tibetan pig interleukin-7 gene and regulation effect in vivo on immune responses of mice

Wan X.P., Wang Z.Z., Yang X., Lang G., Sun W.K., Chen Y-H, Li J.L., Liu R., Gu Y.R., Liu R., Wang Z.Z., Lu X.B., Gao R., Sichuan University, CN

For sake of developing safe and effective technique to deliver and express animal immune gene in vivo to enhance comprehensive immunity of animal against infectious disease, the interleukin-7 gene of Tibetan pig was firstly cloned [...]

Bimolecules in multimodal and multifunctional bioimaging database: potentials and applications

Sharma A., Sharma R., Sharma A., Sharma R., Innovations and Solutions Inc., US

Oligonucleotides are biomarkers in gene expression imaging and proteins for imaging proteomics based on these end product molecules as visible by MRI and PET to give structural and metabolic information in diseased tissue. We compiled [...]

Applied Systems and Synthetic Biology in Micro-Fluidic Biochips

Zeng B.J., Benjoe Institute of Systems Bioengineering, CN

The design of bio-molecular systems within cells, it is a recently achievement of synthetic biology and systems biotechnology [1]. Due to the structurity laws [2] of the synthetic biosystems theory: 1).structure integration, coordinative organization of [...]

Size Matters: The outer diameter of multiwalled carbon nanotubes (MWCNTs) affects gene expression in female fathead minnows (Pimephales promelas)

Carter B.J., Griffitt R.J., Brown-Peterson N., Hammers H.R., Barber D.S., EcoArray, Inc., US

We used oligonucleotide microarrays to examine the gene expression patterns in female fathead minnows (Pimephales promelas) exposed to two different sizes (<8 nm and 50-80 nm outer diameter) and three concentrations (0.1 mg/L, 0.3 mg/L, [...]

Quantum dot (Qdot) labeling of gene expression analysis and single molecule imaging in neurons

Jeromin A., Riley Z., Byrnes E., Parry S., Smith S., Dee N., Jones A., Allen Institute for Brain Science, US

The Allen Brain Atlas1 is the first large scale atlas of gene expression in the mouse brain, using chromogenic in situ hybridization (cISH) of over 20,000 genes.Qdots have excellent potential for muliplex imaging of gene [...]

Galactosidase Gene Expression in Yeast Cells Enhanced by Nanoparticles

Chien S-F, Chen S-H, Lin C-T, Northern Illinois University, US

We report the enhancement of gene expression for rice -galactosidase gene (-Gal) in yeast cells assisted by metal nanomaterials. Au and Ag nanoparticles, and their nanocomposites, silica@Au and silica@Ag were prepared and characterized by UV-vis [...]

Towards the Reconstruction of Gene Regulatory Networks

Tobin F.L., Damian-Iordache V., Greller L.D., SmithKline Beecham, US

Gene expression data in biology is becoming important as the amount and quality of the data rapidly increases. However, the amount generated can be daunting and its direct interpretation is often difficult. The interaction of [...]