Fluorescence – TechConnect Briefs

Photoswitching Nanoparticles Enable Innovative Bioimaging Technologies

Wan W., Li A., Washington State Universoty, US

Nanoparticles have evolved to be the carriers of multiple technologies, which garnished unprecedented power in molecular imaging. For example in bioimaging, a single fluorescent probe is usually lost in the ocean of myriad other molecules [...]

Thorough Characterization of Liposomes by Complementary Light and X-Ray Scattering Techniques

Ragheb R., Bolze J., Taylor G., Tamaddoni N., Griffiths D., Nobbmann U., Malvern Panalytical, US

Liposomes are spherical vesicles with an aqueous core enclosed by one or more phospholipid bilayers or lamellae and are frequently classified based on their size and number of bilayers [1]. They are often used in [...]

Modular Nanoparticle Probes for Personalized in Vitro and in Vivo Imaging of Cancer Cell Populations

Nallathamby P.D., Cowden-Dahl K., Roeder R.K., University of Notre Dame, US

The high mortality and poor prognosis for women diagnosed with ovarian cancer is mainly due to late diagnosis. Improved detection of primary tumors and recurrence after chemotherapy is, therefore, crucial to reduce ovarian cancer mortality [...]

Amplification-free liquid biopsy by fluorescence approach

Uhd J., Taskova M., Okholm A., Astakhova K., University of Southern Denmark, DK

Diagnostics of cancer associated ctDNA, BRAF V600E, KRAS G12D and KRAS G13D respectively. By the use of modern fluorescence microscopy and fluorescently labeled mutation specific LNA/DNA probes. Which resulted in a mutation specific detection.

Uses of Self-assembled Peptide structures doped with electroluminescent compounds

Martins T.D., Ribeiro A.C.C., Souza G.A., Camargo H.S., Cordeiro D.S., Federal University of Goias, BR

Several distinct technological applications can be addressed to self-assembled peptide nanostructures, especially when electroluminescent organic compounds are inserted in these structures. Depending on the preparation methods, these additives can drive the peptide´s self-assembling, resulting in [...]

Carbon NanoDots for Selective Optical Cation Detection

Buiculescu R., Fouskaki M., Chaniotakis N.A., University of Crete, GR

In the present work, custom designed and synthesized carbon nanodots (C-dots) with cation selective functional organic ligands (carboxyl or amino) are used for the optical detection of cations. The ligands on the surface are able [...]

Study on the polymeric nanosphere with imaging functionality

Lin M-H, Liu T.Y., Institute of Biomedical Engineering, National Yang-Ming University, Taipei, 112 Taiwan (ROC), TW

The aim of this research was to develop a novel contrast agent with magnetic resonance (MR) imaging, fluorescent imaging and drug encapsulation functionalities. The zinc oxide (ZnO) nanoparticles and superparamagnetic iron oxide (Fe3O4) nanoparticleswas prepared [...]

Evanescent wave-based particle tracking technique for velocity distribution in extended nanochannel

Kazoe Y., Iseki K., Mawatari K., Kitamori T., The University of Tokyo, JP

We developed a flow measurement technique of velocity distribution in extended nanochannel (10- 1000 nm), using fluorescent tracer nanoparticles and the evanescent wave which penetrates into a liquid medium with an exponential decay from the [...]

Fluorescent Microspheres as Tags for Anti-Counterfeiting of Textiles

Ivanova O.S., Campbell T.A., Virginia Tech, US

The goal of this project is to create an anti-counterfeiting system for textiles that takes advantage of advanced materials and mobile readers. Current anti-counterfeiting systems are challenged in achieving the desired characteristics of lack of [...]

“In-Situ” Monitoring of CdSe/ZnS Quantum Dot Growth During Microwave Synthesis

Zane A., McCracken C., Knight D., Waldman W.J., Dutta P., The Ohio State University, US

The microwave synthesis of CdSe/ZnS quantum dots was observed in real-time using fluorescence spectroscopy for the first time. This technique was used as an efficient way to optimize the temperature and time of the synthesis, [...]