DNA – Page 5 – TechConnect Briefs

Preservation of DNA and Protein Biofunctionality for Bio-MEMS & NEMS Fabrication

Trau D., Jie J., Sucher N.J., National University of Singapore (NUS), SG

Microfabrication processes especially in silicon are not compatible with biomolecules. For example, silicon processing is commonly performed at high temperatures and makes use of aggressive chemicals. Under these conditions biological materials are denaturated or decomposed. [...]

Assembly of DNA Rotaxanes for AFM Based DNA Sequencing

Spadola Q., Qamar S., Lin L., Lindsay S.M., Ashcroft B., Zhang P., Lindsay S.M., The Biodesign Institute at Arizona State University, US

The desire to sequence DNA is fueled by the knowledge that the information locked inside of genomes can help fields as varied as molecular medicine, bioarcheology, forensics, and environmental science. The challenge is to establish [...]

Electrophoretically Actuated Nanoscale Optoentropic Transduction Mechanisms

Sullivan B., Dehlinger D., Zlatanovic S., Esener S., Heller M.J., University of California San Diego, US

We have identified a novel oscillatory optoentropic transduction mechanism that may enable modern communications theory to augment DNA and protein target detection within complex biological samples. More specifically, we have shown that electric field driven [...]

DNA/Cellulose hybrid nanomaterials

Mangalam A., Simonsen J., Benight A.S., Oregon State University, US

One potential advantage of nanotechnology is the ability to engineer bottom-up hierarchical assembly of nanoparticles into functional macroscale materials and devices. The most promising mechanism for accomplishing this is self-assembly. In this project, an advanced [...]

Unique Roles of DNA Wrapped SWNTs: In-situ Fabrication of Self-Doped Polyaniline Nanocomposites

Ma Y.F., Ali S.R., He H.X., Rutgers University, US

Inspired by the remarkable electrical conductivity, the superior mechanical properties of carbon nanotubes(CNTs), and the rich optical, electrical and electrochemical properties of conducting polymers, nanocomposites of conducting polymers and CNTs have been pursued with a [...]

DNA-Based Nanotechnology: Highly Luminescent CdSe – DNA Nanoscale – Engineered Complexes

Kislov V., Artemyev M., Khomutov G., Russian Academy of Sciences, RU

We present some new results within the concept of using DNA molecules as building blocks and nanotemplates for controllable fabrication of various bioinorganic nanostructures due to their unique physical-chemical properties and recognition capabilities and the [...]

Hybrid Nanomaterials for Active Electronics and Bio-Nanotechnology

Wang X., Pandey R.R., Lake R., Ozkan C.S., University of California Riverside, US

We describe self assembly processing of functional carbon nanotubes using single strand deoxyribonucleic acid (DNA) and peptide nucleic acid (PNA) fragments. Previous research has shown the self assembly of carbon nanotubes to quantum dots via [...]

Fabrication of Photonic Transfer DNA-Quantum Dot Nanostructures

Heller M.J., Sullivan B., Dehling D., University of California San Diego, US

Fabrication of Photonic Transfer DNA-Quantum Dot Nanostructures M. J. Heller, B. Sullivan and D. Dehling University of California San Diego; Departments of Bioengineering/Electrical and Computer Engineering; PFBE Bldg, Rm 429: La Jolla CA 92093; 858-822-5699; [...]

Rapid DNA Amplification in Buoyancy Driven Closed Loop Microfluidic Systems

Agrawal N., Ugaz V.M., Texas A&M University, US

Buoyancy driven fluid motion, however, can also occur in closed loop geometries in response to either vertically or horizontally imposed temperature gradients. These systems offer the exciting possibility of generating unidirectional laminar flows along a [...]

Label Free Colorimetric Detection of Single Nucleotide Polymorphisms in Pcr Amplified Genomic DNA

Li H.X., Rothberg L.J., University of Rochester, US

Analysis of DNA is increasingly important in clinical diagnosis, pathology and genetics1, 2. Single nucleotide polymorphisms (SNPs) in genomic DNA are known to be responsible for a number of hereditary conditions3 and cancers4. Nearly all [...]