DNA – Page 2 – TechConnect Briefs

Differentiation of Complex Vapor Mixtures Using Versatile DNA-Carbon Nanotube Chemical Sensor Arrays

Kybert N.J., Lerner M.B., Yodh J.S., Preti G., Johnson A.T.C., University of Pennsylvania, US

Vapor sensors based on functionalized carbon nanotubes (NTs) have shown great promise, with high sensitivity conferred by the reduced dimensionality and exceptional electronic properties of the NT. Critical challenges in the development of NT-based sensor [...]

Surfactant Effect on Intercellular Transport of DNA, Proteins, and Electrolytes

Assan D., Gao X., Lai J.C.K., Leung S.W., Idaho State U, US

Surfactants play a key role on bodily functions at molecular level, such as cell signaling and signal transmission. Their importance in cell survival is well recognized, but the surfactant effect on intermolecular/interfacial mass transport is [...]

Atomistic Simulations of Biomolecules at the Water‐Amorphous Silica Interface: Application to Peptides and DNA Oligomers

Shi B., Shin Y.K., Shin Y.K., Hassanali A., Singer S.J., Ohio State University, US

Realistic modeling of biomolecules near amorphous silica (“glass”), a material commonly used for biomedical device fabrication, is required for device design and evaluation. Our potential model, based on ab initio quantum chemical calculations, is designed [...]

Label-free, Fluorescenece Detection of DNA Nanoparticle Scaffolds

Kell A.J., Tan S., Charlebois I., Boissinot M., Simard B., National Research Council, CA

We have developed a nanoparticle-based DNA biosensor that can detect unlabelled ssDNA with good sensitivity (picomolar concentrations). The biosensor makes use of the optical changes of a cationic polymer interacting with ssDNA versus that of [...]

nano bio computing – synthesis of a nano bio computer using DNA and nanorobots

Vaidyanathan G., Selva B., vickram college of engineering, IN

1) The paper is on interfacing nanotechnology with bio technology to result a nano bio computer. 2) This technology will be capable of replacing the present generation laptops. 3) DNA is used as a memory [...]

Nanocomposites based on Self-assembly of Collagen with DNA

Yadavalli V.K., Pidaparti R.M., Virginia Commonwealth University, US

Collagen is a fibrous protein that undergoes a complex self-organizing process at the nano-, micro-, and macro-scales to form hierarchical fibers. Fiber nano/microstructures are extremely sensitive to biophysical/biochemical environments. Their mechanical properties and anisotropy (macroscale) [...]

Infant HIV and Nanotechnology

Goel N., Sharma R., Pt BDS Post Graduate Institute of Medical Sciences, IN

Background: New methods have emerged in detection and monitoring HIV using nanotechnology techniques but HIV in infants got less attention. Purpose: We report here the Human Immunodeficiency virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) [...]

Gold Nanoparticle-Assisted AFM Study of DNA Damage and Repair

Demir E., Ozber N., Kavakli H., Kizilel S., Rumelifeneri Yolu College of Engineering, TR

The purpose of this research is to investigate gold nanoparticles as a potential scaffold for the characterization of DNA damage and repair using atomic force microscopy techniques. The procedure consists of functionalizing the surface of [...]

Carbon Nanotube Interfaces for Single Molecular Level Bio Sensing

Choi W.B., Vedala H., Roy S., Kim T-H., Florida International University, US

Single molecule detection, aimed both at fundamental investigation and applications, has recently been attracting a lot of attentions. The present set of studies is focused on the design, fabrication and optimization of novel carbon nanotube(CNT) [...]

Characterization of DNA Transport through a Semipermeable Membrane with the Effect of Surfactants

Leung S.W., Bartolin S., Daniels C.K., Lai J.C.K., Idaho State University, US

In current advances of biotechnology, various models of introduction of DNA into cells to alter their gene expression have important biomedical and bioengineering applications. However, the molecular mechanisms underlying how DNA’s cross cell and nuclear [...]