DNA sequencing – TechConnect Briefs

Microfluidics for multiplexing of core needle biopsies

Mojica W.D., Oh K.W., Lee H., Xue X., Furlani E.P., University at Buffalo, US

Image guided biopsies for the procurement of diagnostic tissue has proven to be safe, cost effective and useful. However, the amount of tissue obtained is often diminutive and may be exhausted for conventional diagnostic purposes. [...]

Microfluidics for multiplexing of core needle biopsies

Mojica W.D., Oh K.W., Lee H., Xue X., Furlani E.P., University at Buffalo, US

Image guided biopsies for the procurement of diagnostic tissue has proven to be safe, cost effective and useful. However, the amount of tissue obtained is often diminutive and may be exhausted for conventional diagnostic purposes. [...]

Electrochemistry in nanopore/electrode structures – from pore fabrication to DNA sequencing-by-tunneling

Albrecht T., Imperial College London, UK

I will present results from my research group on nanopore-based single-biomolecule sensor with particular focus on electrode/nanopore structures. To this end, electrochemical concepts can be used for fabrication purposes, as well as for increased temporal [...]

DNA Translocation through a Nanopore

Qamar S., Ashcroft B., Spadola Q., Williams P., Zhang P., Lindsay S., Arizona State University, US

We are developing a technique to sequence the DNA with atomic force microsope. A single strand DNA is threaded to cyclodexrn ring and different forces are abserved as purine and oyrimidin pass through the ring. [...]

Characterization of a Solid State DNA Nanopore Sequencer using Multi-Scale (Nano-to-Device) Modeling

Jenkins J.W., Sengupta D., Sundaram S., CFD Research Corporation, US

The rapid convergence of nanotechnology and biotechnology has generated a need for design tools that can incorporate sufficiently detailed models of the nanoscale molecular phenomena with overarching transport and related effects in microfluidic devices. Currently, [...]