cytotoxicity – Page 2 – TechConnect Briefs

Effect of Dynamic Environment on the Interaction between Nanoparticles and A549 Monolayer

Patel H., Kim H., Kwon S., Utah State University, US

The carbon nanotube (CNT) has been well explored for many proven applications, but very little explored to understand its potential toxic effects. It is crucial to develop viable alternatives to in vivo tests to evaluate [...]

Comparing Cytotoxicity of ZnO Nanoparticles in Exposure to Serum/Serum-free Cell Culture Medium

Hsiao I.L., Huang Y-J, National Tsing Hua University, TW

The aim of this study is to evaluate the influence of serum in cell culture medium on nanotoxicity to human lung epithelial cells (A549). We found nano-ZnO had greater toxicity as it was suspended by [...]

Phagocytizing cells recruitment and activity in response to pulmonary deposition of magnetite particles of different size in nanometer and micrometer ranges

Privalova L.I., Katsnelson B.A., Kuzmin S.V., Degtyareva T.D., Sutunkova M.P., Yeremenko O.S., Khodos M.Y., Kositsina A.N., Malakhova N.A., Glazyrina J.A., Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, RU

It is often maintained that nanoparticles are poorly recognized by host’s defence mechanisms and, specifically, cause weak attraction of phagocytes and are therefore removed from lungs ineffectively. However, intratracheal instillation of water-suspended magnetite nanoparticles caused [...]

Cytotoxicity and genotoxicity of silver nanomaterials

Uyguy B., Mason M.D., Ng A-K., University of Southern Maine, US

Summary We have investigated the cytotoxic effect of dialyzed silver nanoparticles (Ag NPs), PEGylated Ag NPs and silver nanorods on human cultured cells. The cytotoxicity of 24 h treatment with Ag NPs at 0.25, 0.5, [...]

Silicon Dioxide Nanoparticles Exert Dissimilar Cytotoxic Effects on Mammalian Cell Types

Jandhyam S., Lai J.C.K., Lai M.B., Dukhande V.V., Bhushan A., Daniels C.K., Leung S.W., Lai J.C.K., Lai M.B., Idaho State University, US

Applications of nanomaterials (e.g., silicon dioxide (SiO2) nanoparticles) are ubiquitous. Thus, environmental and occupational exposure to these nanoparticles could pose potential health risk. SiO2 microparticles are toxic in animals in vivo and SiO2 nanoparticles are [...]

Cytotoxic Effects of Short Multi-wall Carbon Nanotubes

Agharkar V.A., Bhushan A., Lai J.C.K., Daniels C.K., Idaho State University, US

The applications of carbon nanotubes (CNTs), a novel and important class of nanomaterials, can change paradigms of various research areas. Although biomedical applications of CNTs are increasing, their putative cytotoxicity has not been substantially addressed. [...]

Keywords: cytotoxicity

Effect of Dynamic Environment on the Interaction between Nanoparticles and A549 Monolayer

Comparing Cytotoxicity of ZnO Nanoparticles in Exposure to Serum/Serum-free Cell Culture Medium

Phagocytizing cells recruitment and activity in response to pulmonary deposition of magnetite particles of different size in nanometer and micrometer ranges

Cytotoxicity and genotoxicity of silver nanomaterials

Silicon Dioxide Nanoparticles Exert Dissimilar Cytotoxic Effects on Mammalian Cell Types

Cytotoxic Effects of Short Multi-wall Carbon Nanotubes

Cytotoxicity of bare and PEGylated silica nanoparticles as potential gene-delivery vectors

Biocompatibility of Carbon Nanotubes for Cartilage Tissue Engineering

Differential Cytotoxicity of Metal Oxide Nanoparticles

An Investigation of Cellular Toxicity of Carbon Nanomaterials in African American Breast Cancer Cells