biosensing – TechConnect Briefs

Microsphere Resonators for Biodetection

Echeveria L., Gilmore S., Demory B., Tolfa C., Harrison S., Chavez G., Chang A., Singh P., Bond T., Lawrence Livermore National Laboratory, US

Whispering Gallery Mode microresonators are suitable for biosensing applications as they exhibit large Quality factors (Q) capable of sensing single nanoparticles, while also showcasing a dramatically reduced footprint compared to standard optical sensing techniques. The [...]

Using Nanoparticle Scaffolds to Probe and Enhance the Catalytic Activity of Single and Coupled Enzyme Systems

Hastman D., Chiriboga M., Medintz I., U.S. Naval Research Laboratory, US

The use of nanoparticle (NP) scaffolds for enzymatic systems has proven to be a useful tool for sensing specific enzyme activity as well as enhancing the catalytic rates of these systems. Although, NP-induced enhancement has [...]

Numerical Modelling of a Sinusoidal Grating-Based Surface Plasmon Coupled Emission Biosensor

Sukhotskiy V., Cady N.C., Reddy I.V.A.K., Furlani E.P., University at Buffalo (SUNY), US

We present a full-wave computational model to study the optical behavior of a versatile sinusoidal grating-based surface plasmon-coupled emission (SPCE) biosensor. Surface plasmons (SPs) are coherent oscillations of conduction electrons on a metal surface excited [...]

Giant Enhancement of the Chiro-Optic Response of Chiral Plasmonic Media using Structured Light

Reddy I.V.A.K., Sukhotskiy V., Baev A., Furlani E.P., Prasad P.N., Haus J.W., University at Buffalo (SUNY), US

We propose an approach to achieve a great enhancement and broad spectral tunability of the chiro-optic response of plasmonic metasurfaces by exploiting their interaction with light of complex polarization, endowed with both spin (SAM) and [...]

Analytical Modeling of Microfluidic Cantilever Sensor with Evaporating Ethanol

Marepalli L.K., Sukhotskiy V., K. Reddy I.V.A., Verma A., Furlani E.P., University at Buffalo, US

Resonating microcantilevers are widely used for myriad biochemical sensing applications. Small samples can be characterized for their physical [1], chemical [2], and thermal [3] properties. An example of such a sensor is shown in Fig. [...]

Hydrogel Films with CNT for biosensing applications

Paloma V., Jorge C., Rodolfo E., Iberoamericana University, MX

Hydrogels have been probe to be an amazing material, we present and hydrogel that we formulated with a mix of carbopol 940 and PVA, the selection of this material is because they present a high [...]

Dual Glucose and Lactate Self-powered biosensor

Baingane A., Mburu N., Animanshaun C., Slaughter G., University of Maryland Baltimore County, US

Organ preservation plays a major role in improving the clinical outcome of transplantation. Extracorporeal perfusion systems have been developed for solid-organ transplants (e.g. liver) and recently, investigators have demonstrated incremental improvements in preserving porcine vascularized [...]

Nanocomposites of Nanocrystalline Cellulose for Biosensors Applications

Incani V., Danumah C., Boluk Y., University of Alberta, CA

The development of composite materials is getting increased interest, as they can be a way to achieve adequate sensitivity and stability for biosensors. In this work, we describe the use of a composite material made [...]

Plasmonic nanostructure based biosensing

Patskovsky S., École Polytechnique de Montréal, CA

Plasmonics is quickly becoming a dominant technology in the fields of novel optical devices employing new experimental capabilities of subwavelength metallic nanostructures. In combination with modern nanofabrication technologies which allows preparation of numerous regular patterns [...]

Nanopore/electrode structures for single molecule biosensing

Albrecht T., Imperial College London, UK

In this contibution I will present some of our work on solid-state nanopores, the fabrication of nanopore/electrode structures and how these can be used for single-molecule biosensing applications (DNA, proteins etc.). Specifically, I will introduce [...]