AFM – Page 9 – TechConnect Briefs

Elastic Properties of Aspergillus nidulans Studied with Atomic Force Microscopy

Zhao L., Schaefer D.M., Xu H., Modi S., LaCourse W.R., Marten M.R., Towson University, US

An atomic force microscopy (AFM) was used as a nanoindentor to measure cell wall mechanical properties of the model fungus Aspergillus nidulans in both hyphal and spore forms. Hyphae and spores were immobilized on polylysine-coated [...]

Imaging Bio-electro-mechanics with Scanning Probe Microscopy: Unveiling Nature’s Nanoscale Form and Function

Jesse S., Baddorf A.P., Rodriguez B.J., Gruverman A., Kalinin S.V., Oak Ridge National Laboratory, US

A novel scanning probe technique for studying the physiological structure and electro-mechanical properties of nanoscale biological systems is discussed. The almost universal presence of piezo response in biological material makes this method applicable to a [...]

Interfacial Instabilities in Multilayer Extrusion

Ho K., Lee J.S., Viriyabanthorn N., Sung C., Barry C.M.F., Mead J.L., University of Massachusetts-Lowell, US

Polymeric alternating multilayer laminates have been prepared by coextrusion, utilizing a specially designed feedblock to combine the two incoming materials from different extruder. Layer multiplying elements (LME) were used to split the melt stream, divide [...]

Phase Identification and Elastic Property of Blend Copolymer Characterized by Force Modulation Microscopy and Force-Distance Curve

Kang B., Lee J.S., Pham L., Sung C., University of Massachusetts-Lowell, US

The technique of polymer blending has been used to create new types of polymers with desirable properties in the past decade. Force Modulation Microscopy (FMM) provides a local contrast due to the local elasticity difference [...]

The Measurement of Ferroelectric Thin Films Using Piezo Force Microscopy

Cain M.G., Dunn S., Jones P., National Physical Laboratory, UK

The use of Atomic Force Microscopy to evaluated the surface properties of ferroelectric thin films is often associated with poor signal to noise ratio images and quantitative analysis is not possible. In this presentation the [...]

Amplification of Protein Adsorption on Micro/Nanostructures for Microarray Applications

Ivanova E.P., Alekseeva Y.V., Pham D.K., Filipponi L., Nicolau D.V., Swinburne University, AU

The fabrication and operation of biodevices require the accurate control of the concentration of the bioactive molecules on the surface, as well as the preservation of their bioactivity, in particular proteins that have a significant [...]

Functional Nanoarrays for Protein Biomarker Profiling

Lynch M., Mosher C., Huff J., Nettikadan S., Xu J., Henderson E., BioForce Nanosciences, Inc., US

The success of microarrays for analyzing nucleic acid and, more recently, protein-protein interactions illustrates the advantages of bioassay miniaturization. However, the current level of miniaturization of useful bioanalytical tools still creates limits in terms of [...]

Size Effect on the Elastic Modulus of Nanomaterials as Measured by Resonant Contact Atomic Force Microscopy

Cuenot S., Demoustier-Champagne S., Frétigny C., Nysten B., Université catholique de Louvain, BE

The elastic modulus of metallic nanowires and polymer nanotubes was measured using a novel method called resonant contact atomic force microscopy. The direct application of a normal load to the contact was obtained using a [...]

System Identification for Motion of Proteins Using an AFM-based Nanorobotic Manipulation

Park J., Kim B-K., Kim D-H., Kim B-K., Kim D-H., Lee K-I., Korea Institute of Science and Technology, KR

It is greatly important to understand the mechanics of AFM-based nanorobotic manipulation for efficient and reliable handling of nanoparticles. Robust motion control of an AFM-based nanorobotic manipulation is much challenging due to uncertain mechanics in [...]

Biologically Inspired Controls over Assembly of Crystalline Nanostructures

De Yoreo J.J., Orme C.A., Qiu R., Dove P.M., Lawrence Livermore National Laboratory, US

By utilizing small molecules and proteins to modulate crystal nucleation and growth, living organisms produce single nanocrystals and nanocrystal composites that exhibit control over the location, phase and crystallographic orientation of the nuclei, as well [...]