Yu H. – TechConnect Briefs

Amplified On-Chip Fluorescent and Colorimetric Detection of DNA and RNA Hybridization by Surface-Initiated Enzymatic Polymerization

Tjong V., Yu H., Hucknall A., Chilkoti A., Duke University, US

We present a new on-chip, isothermal signal amplification technique for direct detection of unmodified DNA and RNA on microarrays using terminal deoxynucleotidyl transferase (TdT), a template-independent DNA polymerase that catalyzes the sequential addition of deoxynucleotides [...]

Magnetic Nanotag-based Immunoassay for Multiplex Mycotoxin Detection

Mak A.C., Osterfeld S., Yu H., Wang S., Davis R.W., Jejelowo O.A., Pourmand N., Stanford University, US

Rapid, sensitive and multiplexed measurement is vital in molecular diagnostics such as cancer diagnosis and pathogens detection. While highly specific and sensitive, traditional immunochemical assays such as enzyme-linked immunosorbent assays (ELISAs) often require expensive read-out [...]

Effects of the Building Block on the Morphology and Properties of Porous CdSe Nanostructured Framework

Yu H., Bellair R., Kannan R., Brock S., Wayne State University, US

A major challenge in designing and making potentially valuable nanostructures is to find suitable ways to effectively tune their properties and function. Recent work in our lab has demonstrated a powerful strategy to engineer the [...]

Single dot luminescence characteristics of CdSe/ZnS core-shell structured quantum dots with different ligands

Yu H., Song N.W., Moon D.W., Shin S.K., Korea Research Institute of Standards and Science, KR

Chemical derivatizations with different ligands were perfomed on CdSe/ZnS core-shell quantum dots (QDs). The role of ligands serves to increase water solubility and bio-compatibility of QDs for in-vivo biomedical fluorescence imaging. These QDs were synthesized [...]

Direct Scanning Laser Writing of 3D Multilayer Microstructures

Yu H., Li B., Zhang X., Boston University, US

Material processing with lasers is an expanding field since it not only makes manufacturing cheaper, faster, cleaner, and more accurate but also opens up entirely new technologies and manufacturing methods that are simply not available [...]