Khan R.A. – TechConnect Briefs

Antibiocorrosive Woods and Plastics Nanomaterials :Arsonium triiodides and Silicon Organic matrix

Khan R.A., Sharma R., Manav Rachna International University, IN

A search of anticorrosive with antibacterial property of compounds motivated us to synthesize nanomaterials with quaternary compounds. The arsonium triiodides [(Ph3AsCH2I]I3 and [(i-Bu)3AsCH2I]I3 nanomaterials have been synthesized and characterized. The x-ray structures of [(Ph3AsCH2I]I3 and [...]

Minimal-dose cancer chemotherapy: Anti-cancer drugs loaded nanodevices towards time, site, and organ-specific releases for development of personalized nanomedicine

Khan R.A., Newati S.J., Singh V.M., Sachdeva S., Sharma R., Manav Rachna International University (MRIU), IN

The objective of the present study was to develop a site specific, time controlled and organ targeted anti-cancer drug delivery nanosystem comprising of nano-particles of polymeric origins for treatment of cancer in minimum dose regimen. [...]

An Intracranial Neurocompatible Nanocomposite Polymeric Device for the Chronic Management of AIDS Dementia Complex

Khan R.A., Harilall S-L., Pillay V., Choonara Y.E., du Toit L.C., Modi G., Naidoo D., Iyuke S., Integral University, IN

This study focused on the design, biometric simulation and development of a biodegradable Composite Intracranial Nano-enabled Device (CIND) for the intracranial delivery of zidovudine (AZT) in the treatment of AIDS Dementia Complex (ADC), a common [...]

Iron oxide nanoparticles reinforced self-assembled monolayers of cystamine for use in enzymatic biosensor development

Newati S.J., Singh V.M., Sachdeva S., Khan R.A., Manav Rachna International University (MRIU), IN

The immobilization of biomolecules on solid support is crucial component in fabrication of biosensors. The self assembled monolayers (SAM) can be used for fabrication of the biosensor-component that allows chemically reactive functional group manipulations for [...]

Newer Methods of Nanoparticle Synthesis: Nitroimidazole properties with Nanometal oxides in Polymer Cages

Khan R.A., Sharma R., Florida State University, IN

Nitroimidazoles are radiosensitizers and hypoxia detecting chemosensitizers. Intially nitroimidazoles were single dose antibiotic drugs. Recently, nitroimidazole derivatives have emerged as multifunctional “drug-biomarker monitors” chemical compounds with importance in treatment of tumors, monitoring hypoxia and safer [...]