Dye Coded Nanoparticle as SERRS Labels for Ultrasensitive Detection of Proteins and Antibodies

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We have developed a novel surface enhanced resonance Raman scattering (SERRS) detection method that is amenable for almost any biological target. By utilising the information rich spectrum obtained from SERRS we show that we can simultaneously screen multiple analytes with efficient discrimination between targets. The method has been applied to a number of proteomic targets in several assay formats. We have used ultra-fast Raman line mapping which allows us to rapidly screen large areas with high selectivity.

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Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2008: Life Sciences, Medicine & Bio Materials – Technical Proceedings of the 2008 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: June 1, 2008
Pages: 259 - 261
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech
Topicss: Biomaterials, Materials Characterization & Imaging
ISBN: 978-1-4200-8504-4