University of Rochester – TechConnect Briefs

Permeability and protein separations: functional studies of porous nanocrystalline silicon membranes

Snyder J., Kavalenka M., Fang D., Striemer C., Fauchet P., McGrath J., University of Rochester, US

We have developed an ultrathin (15nm) freestanding nanoporous silicon based membrane [1]. This new material, termed porous nanocrystalline silicon (pnc-Si), is fabricated using standard photolithography techniques. Pore sizes can be tuned in a thermodynamically driven [...]

Manufacturable nanoscale membranes – material development and biological separations

Gaborski T.R., Striemer C.C., Snyder J.L., Fang D.Z., Fauchet P.M., McGrath J.L., University of Rochester, US

We have developed a new class of ultrathin porous nanocrystalline silicon (pnc-Si) membranes using inexpensive and scalable silicon fabrication techniques. Pnc-Si is formed from a deposited amorphous silicon thin film, where nanoscale pores are introduced [...]

Protein binding to particle surfaces determines intracellular interaction and uptake kinetics

Ehrenberg M., McGrath J.L., University of Rochester, US

People are exposed to nanoparticles in from varying sources and in many ways. The goal of our research is to simplify this diverse problem by establishing a systematic understanding of the properties of particles that [...]

Label Free Colorimetric Detection of Single Nucleotide Polymorphisms in Pcr Amplified Genomic DNA

Li H.X., Rothberg L.J., University of Rochester, US

Analysis of DNA is increasingly important in clinical diagnosis, pathology and genetics1, 2. Single nucleotide polymorphisms (SNPs) in genomic DNA are known to be responsible for a number of hereditary conditions3 and cancers4. Nearly all [...]

Rapid DNA Sequence Identification based on Electrostatic Interactions with Unmodified Gold Nanoparticles

Li H.X., Rothberg L.J., University of Rochester, US

Sequence-specific detection of DNA play more and more important role in clinical diagnosis and molecular biology research. Most assays identify specific sequence through hybridization of an immobilized probe to the target analyte after the latter [...]

Smart Bandage – A Hydrogel Supported Optical Microcavity Sensor

DeLouise L.A., University of Rochester, US

Developing new medical diagnostic technologies that can be used in the home for early detection and disease prevention is a central focus at the University of Rochester Center for Future Health. This paper is concerned [...]

Nanocrystalline Silicon Superlattices for Nanoelectronic Devices

Tsybeskov L., University of Rochester, US

This paper provides a brief introduction to a novel nanostructured system consisting of ordered layers of Si nanocrystals separated by atomically flat and chemically abrupt layers of amorphous silicon dioxide with thickness of several nanometers. [...]

Diffusion Induced Stresses in Microstructures of MEMS

Yang F., University of Rochester, US

The diffusion-induced stresses in silicon wafers were studied. The effect of local electric field on dopant diffusion was considered in the diffusion equation. Only one-dimension problem with a constant surface dopant concentration was investigated. The [...]

Modeling of On-Chip Simultaneous Swithcing Noise in VDSM CMOS Circuits

Tang K.T., Friedman E.G., University of Rochester, US

On-chip simultaneous switching noise (SSN) has become an important issue in the design of power distribution networks in current VLSI/ULSI circuits. An analytical expression characterizing the simultaneous switching noise voltage is presented here based on [...]