University of Louisville – Page 2

Photoconductivity of Reduced Graphene Films

Loomis J., Panchapakesan B., University of Louisville, US

In this paper, we report large photocurrents in air-assisted depositions of reduced graphene films (derived from reduced single layer graphene oxide) upon illumination with near-infrared (NIR) light. NIR-induced charge carrier generation and subsequent separation at [...]

Mechanical Properties of Reduced Graphene Polymer Composites

Xu P., Panchapakesan B., University of Louisville, US

In this paper, we report load transfer and mechanical properties of chemically derived single layer graphene (SLG) as reinforcements in poly (dimethyl) siloxane (PDMS) composites. Shear mixing reduced graphene sheets in polymers resulted in a [...]

Targeted Cancer Therapy by Immunoconjugated Gold-Gold Sulfide Nanoparticles Using Protein-G as a Cofactor

Sun X.H., Zhang G.D., Patel D., Gobin A.M., University of Louisville, US

Gold-gold sulfide nanoparticle (GGS-NP) with controllable near infrared (nIR) absorption was synthesized from a simple reaction of chloroauric acid and sodium thiosulfate. Through PEGylated recombinant Protein-G (ProG), ProG-conjugated GGS-NPs for antibody capture by Fc domain [...]

Ultralow Detection of Bio-markers using Gold Nanoshells

Patel D., Zhang G., Sun X., Gobin A.M., Keynton R.S., University of Louisville, US

The focus of this project is to improve the detection of antigen/biomarkers/viral vectors using gold nanoshells (GNS). The assay used in this project is based on aggregation of GNS in presence of antigen or viral [...]

A Novel High Yield Process for Gold Sulfide Nanoparticle Synthesis via Shifting Equilibrium of Self-Assembly Reaction

Patel D., James K., Zhang G., Gobin A.M., University of Louisville, US

This project is focused on the scale up of gold-gold sulfide (GGS) nanoparticles with desired near infrared peak (nIR) that can be used for therapeutic applications. By combining published methods for 1-step self-assembly of GGS [...]

Near-Infrared Light Induced Mechanical Responses in Single-to-Few Layer Graphene

Loomis J., King B., Panchapakesan B., University of Louisville, US

Layer dependent physical responses of graphene-based polymer composites to near-infrared (NIR) light are reported. Thin film polymer composites were fabricated and compared utilizing both single layer graphene and few layer graphene (~5 layers). NIR-induced axial [...]

Photomechanical Response in Graphene Nanoplatelet Composites

Loomis J., King B., Burkhead T., Xu P., Bessler N., Terentjev E., Panchapakesan B., University of Louisville, US

Large light-induced reversible and elastic responses of graphene nanoplatelet (GNP) polymer composites are reported. Homogeneous mixtures of GNP/polydimethylsiloxane (PDMS) composites (0.1–5 wt%) were prepared and their near-infrared (NIR) mechanical responses studied with increasing pre-strains. Using [...]

Carbon Based Dimensional Composites

Loomis J., King B., Panchapakesan B., University of Louisville, US

Dimensional dependence of mechanical response in carbon nanostructure composites to near-infrared (NIR) light are reported. Using polydimethylsiloxane, composites were fabricated with one-dimensional multi-wall carbon nanotubes (MWCNTs), two dimensional single-layer graphene, two and a half-dimensional graphene [...]

Carbon Nanotubes as Molecular Nanocarriers for Antibody Delivery and Photothermal Ablation of Breast Cancer Cells

Panchapakesan B., Wickstrom E., University of Louisville, US

In this paper, the utilization of carbon nanotubes as nanocarriers for antibody delivery to IGF1R and HER2 surface receptors and selective thermal ablation of breast cancer cells is presented. IGF1R and Her2 surface receptors are [...]

Nanotube Biosensor Arrays for Detection of Molecular Surface Markers in Breast Cancer Cells

Panchapakesan B., Wickstrom E., University of Louisville, US

Recent reports have shown that nanoscale electronic devices can be used to detect a change in electrical properties when receptor proteins bind to their corresponding antibodies functionalized on the surface of the device, in extracts [...]