US – Page 96 – TechConnect Briefs

Combating Dental Caries Via Restorative Materials Containing Antibacterial and Remineralizing Nanoparticles

Melo M.A.S., Cheng L., Zhang K., Weir M.D., Chow L.C., Antonucci J.M., Lin N.J., Lin-Gibson S., Lin-Gibson S., Xu H.H.K., University of Maryland Dental School, US

Dental caries is a wide spread public health problem, despite much effort in health promotion. Caries at the margins of restorations has been the main reason for failure. The development of direct-filling dental materials with [...]

Nanocrystalline gold-based hydrogen sulfide (H2S) sensor from M13 bacteriophage template

Moon C.H., Zhang M., Yan Y., Myung N.V., Haberer E.D., University of California Riverside, US

Bio-templated assembly of inorganic materials is a promising technique for facile bottom-up assembly of complex and unique nanostructures at ambient conditions. Here, viral-templated nanocrystalline gold nanowires were synthesized for use in highly sensitive H2S sensors [...]

Allosteric pathway formation in globin proteins explored with network analysis models

Pfeffer J., Woods K.N., Carnegie Mellon University, US

In the context of drug design and protein engineering, understanding the nature of allosteric networks is of particular interest. A pre-condition for successfully developing a rational design of proteins that incorporates allostery is the capability [...]

Three-Dimensional Bioprinted Biomimetic Nanocomposite Scaffolds for Osteochondral Regeneration

Castro N.J., Zhang L.G., The George Washington University, US

The current work focused on the manufacture of a three-dimensional biphasic nanocomposite scaffold for osteochondral regeneration. Extrusion-based 3D printing in combination with ultraviolet light induced photocrosslinking allowed for good integration of two disparate polymeric materials [...]

Enhanced Mechanical and Cytocompatibility Properties of Novel 3D Printed Osteochondral Scaffolds

Holmes B., Zhang LG., The George Washington University, US

A series of novel 3D osteochondral computer aided models were designed including a homogenous cross-hatched structure, a bi-phasic structure consisting of a cross hatched pattern and an intersecting rings structure, and a biphasic “key” model [...]

Assessment by Ames Test and Comet Assay of Toxicity Potential of Polymers Used to Develop a Field Capable Biosensor

Hebert A., Torosian S., Gleason K., Food and Drug Adminstration, US

Current methods of detecting food-borne pathogens take days to show and confirm results. There is a need for devices that decrease detection time. A field-capable rapid-detection device is being developed and in this study it [...]

Triggered Assembly of Functional Protein Microdomains in the Cytosol

MacKay J.A., Pastuszka M.K., Shi P., Dhandhukia J., University of Southern California, US

Biology is unparalleled in the replication of complex structures with diverse functions on the molecular and cellular scale. By using biological materials to assemble structures, process information, and harness energy, the emerging field of synthetic [...]

Reduced bacterial attachment on surface modified hydrophobic fabric surface: a possible approach for safety enhanced packaging material

Chaudhari A.A., Rangan K.K., Sudarshan T.S., Singh S.R., Pillai S.R., Alabama State University, US

In the present study, three surface modified fabrics were investigated for their bacterial attachment properties using Salmonella enterica serovar Typhimurium (gram –ve) and Staphylococcus aureus (gram+ve) bacteria. Our results indicate that surface modified fabric show [...]

Characterization of silver-coated carbon nanotubes dispersed in a specifically formulated dispersant – NanoSperse AQ®

Chaudhari A.A., Singh S.R., Pillai S.R., Alabama State University, US

Silver-coated carbon nanotubes (AgCNTs) are well documented for their antibacterial properties. However, aqueous dispersions of AgCNTs could be less effective against bacteria due to their tendency to agglomerate when re-suspended in water. In this study [...]

Novel silicon microdosimeter based on 3D cylindrical structures

Guardiola C., Carabe-Fernández A., Gomez F., Pellegrini G., Fleta C., Quirion D., Lozano M., University of Pennsylvania, US

A new design of a solid-state-detector based on silicon microfabrication is provided in this work in order to create a novel microdosimeter. This microdosimeter improves the performance of existing microdosimeters using three-dimensional microfabrication technology development. [...]