Silver-coated carbon nanotubes (AgCNTs) are well documented for their antibacterial properties. However, aqueous dispersions of AgCNTs could be less effective against bacteria due to their tendency to agglomerate when re-suspended in water. In this study we have characterized AgCNTs dispersed in Nanosperse AQ® (dAgCNTs) from NanoLab Inc. and water dispersed AgCNTs (wAgCNTs), and compared their bactericidal activity against Salmonella enterica serovar Typhimurium and Escherichia coli. dAgCNTs were homogenously dispersed as compared to wAgCNTs which formed agglomerates even after repeated sonnication. The minimum inhibitory concentrations (MIC) of dAgCNTs (31-15 µg/ml) were approximately three folds lower compared to wAgCNTs (100-62.5 µg /ml) against both Salmonella enterica serovar Typhimurium and Escherichia coli. Our results indicate that dispersion of AgCNTs using an appropriate dispersion technique may result in a relatively stable and homogenous solution of AgCNTs, thereby improving their anti-bacterial activity.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational & Photonics
Published: June 15, 2014
Pages: 227 - 230
Industry sectors: Advanced Materials & Manufacturing | Medical & Biotech