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Glucometers to Detect for Heart Attack

Haik Y., Qablan A., Zwolinski A., Chen C-J., Florida State University, US

Acute Myocardial Infarction (AMI), commonly referred to as a heart attack, is a disorder in which damage to an area of heart muscle occurs because of an inadequate supply of oxygen to that area leading [...]

Modeling of Dielectrophoresis for Handling Bioparticles in Microdevices

Yao G.F., Flow Science Inc., US

Dielectrophoresis can be used to trap and position bioparticles efficiently and sucessfully in BioMEMS devices. This paper present a computational model to simulate this process. In particular, the model will solve for electric potential distribution, [...]

Characterization of Micropumps for Biomedical Applications

Haik Y., Hendrix J., Kilani M., Galambus P., Chen C-J., Florida State University, US

A novel class of micro pump was developed at the Biomagnetic Engineering Lab at Florida State University. The pump operates by utilizing the viscous effects that are dominant the micro scale and by spinning a [...]

Resolved Particle Simulations of Microsphere/Cell-based Bioanalytic Systems

Pant K., Romanowicz B.F., Sundaram S., CFD Research Corporation, US

Microsphere and cell-based assays are emerging as the platform of choice for rapid quantitation of biomolecular interactions in bioagent detection, clinical diagnosis, drug therapy, etc. [1,2] Traditional assay designs have been driven by expensive trial-and-error [...]

Development of an Advanced Simulation System for the Analysis of Particle Dynamics in LASER based Protein Ion Sources

Hieke A., Ciphergen Biosystems, Inc., US

An advanced multi-physics simulation system henceforth referred to as GEMIOS (Gas and Electromagnetic Ion Optical Simulator) has been implemented which allows the computation of 3D trajectories and energy exchange of ion beams/clouds under the influence [...]

A Monte Carlo Study of a Model of Globular Protein Nanoparticles

Pagan D.L., Gracheva M.E., Gunton J.D., Lehigh University, US

We explore the metastable fluid-fluid coexistence curve of the modified Lennard-Jones model of globular proteins of ten Wolde and Frenkel [4]. Using grand canonical Monte Carlo simulations along with mixed-field finitesize scaling and histogram rewighting, [...]

Self Assembly of Globular Protein Nanoparticles

Shiryayev A., Gunton J.D., Lehigh University, US

A continuum model of the self-assembly of globular protein nanoparticles proposed by Talanquer and Oxtoby (J. Chem. Phys. 109, 223 (1998)) is investigated numerically, with particular emphasis on the region near the metastable fluid-fluid coexistence [...]

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