US – Page 373 – TechConnect Briefs

Nanofluidic Size Exclusion Chromatograph for In Site Macromolecular analyses

Choi D., Grunthaner F., Feldman S., Svehla D., Jet Propulsion Laboratory/California Institute of Technology, US

We are developing a nanofluidic size exclusion chromatograph (nano-SEC) system that can be incorporated into miniature lab-on-a-chip devices which will provide detailed information on the geochemical and biological history of soil, ice, and water samples [...]

Fast mixing using the Shear Superposition Micromixer

Bottausci F., Cardonne C., Mezic I., Meinhart C., university of california, santa barbara, US

We present new experimental results showing high efficiency mixing procedures for an active shear superposition micromixer (SSM). This micromixer consists of a main mixing channel where unmixed fluids are perturbed by jet flows emanating from [...]

Fabrication of Microfluidic Cells with Liquid Core Waveguide and 1,1’-Oxalydiimidazole Chemiluminescence Detection

Lee J-H., Tartaglia A., Schlautman M.A., Carraway E.R., Clemson University, US

We have developed simple and inexpensive microfluidic cells (inner diameter: 100 _m) based on the principles of liquid core waveguide (LCW) and rapid 1, 1’-oxalyldiimidazole derivative chemiluminescence (ODI-CL) reactions. The microfluidic cells devised in this [...]

Valving in Microchannels via Electrodeposition on Solid Electrolytes

Kozicki M.N., Maroufkhani P., Mitkova M., Arizona State University, US

We have recently developed a reliable and inexpensive way to electrically regulate flow through microchannels via a structure that can be made using readily available microfabrication techniques. We use an electrical signal to stimulate silver [...]

Characteristics of Bacterial Pumps in Microfluidic Systems

Kim M-J, Breuer K.S., Brown University, US

In this paper we show that (i) the flow-deposition of bacteria can successfully create a live bacterial carpet to generate local fluid motion inside a microfabricated system; (ii), that the carpet-activated microfluidic system can be [...]

Multiobjective Evolution Strategies for Optimization of Microfluidic Mixing

Mautner T., Consultant, Technology Development, US

microfluidics, lattice Boltzmann, opimization, biosensor Summary: An investigation has been performed to determine the effect of various surface temperature distributions on the mixing of a binary fluid. Lattice Boltzmann simulations were conducted on a binary [...]

Investigation of Volume of Fluids (VOF) Method and System Models for Design of Microfluidic Ink Delivery Apparatus for Dip Pen Nanolithography (DPN)

Banerjee D., Texas A&M University, US

DPN™ is a versatile technology that leverages Scanning Probe Microscopy for applications in biotechnology, photomask repair, molecular-electronics, nano-electronics and mask-less lithography(1). In earlier studies (2) the DPN process was augmented for biotechnology applications (genomics, proteomics) [...]

Fast and Sensitive DNA Hybridization Through Micro- Fluidics

Marafie A.H., Madou M.J., University of California Irvine, US

The research target for DNA hybridization through micro-fluidics is to achieve a fast and very sensitive hybridization reaction by investigating the effect of different pertinent parameters using computational and experimental methods. The mathematical model that [...]

Thermal Modulation and Instability of Viscous Microjets

Furlani E.P., Eastman Kodak Company, US

Liquid microjets are inherently unstable and can be broken into droplets by various means including the modulation of pressure, velocity, and/or fluid properties. In this presentation we discuss the controlled breakup of viscous microjets via [...]

A Computational Model for the Design of ElectroWetting On Dielectric (EWOD) Systems

Bedekar A.S., Jenkins J.W., Sundaram S., CFD Research Corporation, US

Microfluidics has enabled the development of integrated lab-on-a-chip (LoC) devices for use in a clinical diagnostics, high throughput screening, drug discovery, biodefense and environmental monitoring. Although most microfluidic devices are based on continuous flow of [...]