US – Page 149 – TechConnect Briefs

Design of a noninvasive blood glucose Sensor

Wang-Roveda J.M., Nguyen D., Nguyen H.V., Nguyen D., Nguyen H.V., MIAO LLC, US

25.8 million Americans (8.3% of the U.S. population) have Diabetes Mellitus with an annual increase rate of 1.3 million cases 1. There is 1.9 million new cases in 2010 1. Diabetes also results in kidney [...]

DNA detection using Laser Transmission Spectroscopy

Li F., Mahon A.R., Barnes M.A., Egan S., Feder J., Lodge D.M., Hwang C.-T., Schafer R., Ruggiero S.T., Tanner C.E., University of Notre Dame, US

Laser transmission spectroscopy (LTS) is a new quantitative and rapid technique for measuring the size, shape, and number of nanoparticles in suspension. We report on the application of LTS as a novel detection method for [...]

Continuous Sensing of blood by dark-field microscopy and surface-enhanced Raman Spectroscopy

Henry A.-I., Sharma B., Sagle L.B., Van Duyne R.P., Northwestern University, US

Surface-enhanced Raman spectroscopy (SERS) is a rapid, label-free technique with multiplexing capabilities, making it very relevant for the sensitive real-time detection for biomedical applications , , . Demonstration of in vivo glucose detection with unprecedented [...]

Magneto-plasmonic Nanoplatforms for Enhanced Bioimaging and Photothermal Cancer Therapy

Kopwitthaya A., Ohulchanskyy T.Y., Jeon M., Law W-C., Xie Q., Chada R.R., Xue X., Furlani E.P., Kim C., Prasad P.N., University at Buffalo (SUNY), US

Multifunctional nanoplatforms are finding increasing use in a host of emerging applications in the fields of biophotonics and nanomedicine where they are used to target, probe, image and treat tissue at the cellular and subcellular [...]

A Metallofullerene Nanoparticle Platform for Imaging and Treatment of Glioblastoma Multiforme Tumors

Dorn H.C., Zhang J., Fatouros P., Shultz M.D., Wilson J.D., Virginia Polytechnic Institute and State University, US

Glioblastoma multiforme (GBM) brain tumors occur as masses with infiltrative margins that are extremely invasive. GBMs result in a high recurrence rate with a poor prognosis for patients who are newly diagnosed with only an [...]

Sample Preparation by On-Chip Dielectrophoretic Separation and Concentration of Viable, Non-Viable and Viable but Not Culturable (VBNC) Escherichia coli

Packard M., Shusteff M., Alocilja E., Michigan State University, US

Although bacterial culture remains the gold standard for detection of viable bacteria in environmental specimens, the typical time requirement of twenty-four hours can delay and even jeopardize appropriate determination. In addition, culture is incapable of [...]

Ultralow Detection of Bio-markers using Gold Nanoshells

Patel D., Zhang G., Sun X., Gobin A.M., Keynton R.S., University of Louisville, US

The focus of this project is to improve the detection of antigen/biomarkers/viral vectors using gold nanoshells (GNS). The assay used in this project is based on aggregation of GNS in presence of antigen or viral [...]

Gold nanoparticles as a tool to detect UTI and their cytotoxic effects in DU-145 cells

Vedantam P., Tzeng J., Brown A., Podia R., Staley K., Rao A., Clemson University, US

The abstract includes a brief description of how two different kinds of E.coli can have different binding specificities and detection of such organisms with sugar functionalized nanoparticles can be used as a biodiagnostic technique.

A Fully Automated Method to Create Monte-Carlo MOSFET Model Libraries for Statistical Circuit Simulations

Wang J., Trombley H., Watts J., Randall M., Wachnik R., IBM Semiconductor Research and Development Center, US

As the MOSFET continues to shrink, device-to-device variations become increasingly important. Therefore, it is critical to develop accurate, Monte-Carlo (MC) models that capture various device variations to allow statistical circuit simulations. To model the global [...]

On the Variability of HfOx RRAM: From Numerical Simulation to Compact Modeling

Guan X., Yu S., Wong H.S.P., Stanford University, US

The trap-assisted conduction and filamentary switching mechanisms of the HfOx based resistive memory are studied. A numerical simulator is developed to reproduce the experimental I-V curves. Comparison with experiments shows that the cycle-to-cycle variation in [...]