US – Page 112 – TechConnect Briefs

Framework for Quantitative Exposure Assessment of Nanostructured Materials in Occupational Settings

Kreider M.L., Unice K.M., Panko J.M., ChemRisk, US

The purpose of this work was to provide a framework for assessing potential for risk and exposure to nanostructured materials in occupational settings. In doing so, we evaluated the characteristics of amorphous silica and carbon [...]

Occupational Safety and Health Management Systems for the Safe Commercialization of Nano-enabled Products

Heidel D., Segrave A., Baker J., Bureau Veritas North America, US

The value of an occupational health and safety management systems (OHSMS) approach for the safe synthesis of engineered nanoparticles and safe commercialization of nano-enabled products will be presented. An OHSMS framework integrates continual H&S improvement [...]

Analysis of Factors Associated with the Releasability of Carbon Nanotubes (CNTs) from Materials Containing Nanocomposites

Kovochich M., Avanasi R., Madl A.K., ChemRisk, US

Carbon nanotubes (CNTs)in composites are currently being used in applications ranging from basic consumer goods to critical national defense technologies; however, concerns have been raised regarding the potential for exposure and health risk CNTs due [...]

Nanoparticle Characterization and Analysis of Airborne Titanium Dioxide in Powdered Cosmetics

Cavaliere M.R., Compton S.P., MVA Scientific Consultants, US

In this study, several powdered cosmetic products were purchased and evaluated for the presence of TiO2 nanoparticles first by automated particle sizing using scanning electron microscopy (SEM) with chemical typing by energy dispersive spectroscopy (EDS) [...]

Risk Ranking Framework to Assess the Health Hazard of Nanomaterial-Containing Products in an Industrial and Consumer Application Setting

Madl A.K., Unice K., Kreider M., Kovochich M., Bebenek I.G., Abramson M.M., ChemRisk, US

The unique combination of size, structure, morphology, physical/chemical characteristics, and quantum properties of nanomaterials, presents a challenging platform in understanding the potential hazards and health risks of engineered nanomaterials and the products that utilize these [...]

Surface Chemical Transformations of UV Irradiated Silica-Epoxy Nanocomposites

Gorham J.M., Nguyen T., Bernard C., Stanley D., Holbrook R.D., National Institute of Standards and Technology, US

Silica nanoparticles (SiNPs) incorporated into a polymeric matrix, or silica nanocomposites (NCs), are used in a wide variety of commercially available products in numerous natural and artificial environments. Environmental factors, such as ultraviolet (UV) light, [...]

Quantitative Assessment of Nanoparticle Induced Oxidative DNA Damage Using Isotope Dilution Mass Spectrometry

Petersen E.J., Marquis B.J., Jaruga P., Dizdaroglu M., Nelson B.C., National Institute of Standards and Technology, US

Hyphenated mass spectrometry (gas chromatography/mass spectrometry) techniques have been employed as one of the primary analytical tools for investigating the effects of ionizing radiation, chemical/biological carcinogens and oxygen derived free radicals on the induction and [...]

“Just Add Water” – “Instant” singly-dispersed suspensions of silver nanoparticles on demand

MacCuspie R.I., National Institute of Standards and Technology, US

The rapid pace of development of new nanomaterials and new applications has also attracted much attention from the environmental health and safety (EHS) risk assessment community. Subsequently, calls for well-characterized common test materials from a [...]

Bio-compatibility of silver nanomaterials using the embryonic zebrafish bioassay

Fisher J.A., Tanguay R.L., Oregon State University, US

The bio-compatibility of silver nanomaterials (AgNP) is currently of great interest to regulators and health and safety professionals because it is a material that has the potential to reach mass populations. Four well characterized (Harper [...]

Entry of Short Multi-Wall Carbon Nanotubes into Dorsal Root Ganglion (DRG) Neurons Induces Cell Death

Lai J.C.K., Gao W., Bhushan A., Bearden S.E., McDougall L., Leung S.W., Idaho State University College of Pharmacy, US

Carbon nanotubes (CNTs) have found their way into diverse industrial and biomedical applications because of their unique physico-chemical properties. However, the human health impact of exposure to CNTs is unknown. Our recent and ongoing studies [...]