US – Page 11 – TechConnect Briefs

Enhancement of Effects of Chitosan and Nanoparticles on Pancreatic Cancer Cells by Combination Treatments with the Anti-Cancer Drug Adriamycin

Lai J.C.K., Gao W., Bhushan A., Leung S., Idaho State University College of Pharmacy, US

Because of chitosan’s roles in biomedical applications, this study investigated the effects of chitosan, chitosan in combination with silver or gold nanoparticles, and chitosan with nanoparticles and Adriamycin, Methotrexate or Cisplatin on human PANC-1 pancreatic [...]

Cytotoxic Effects of Short Multi-Wall Carbon Nanotubes on Pancreatic Cancer Cells

Lai J.C.K., Desai V., Zhang Y., Bhushan A., Leung S., Idaho State University College of Pharmacy, US

Although carbon nanotubes (CNTs) are increasingly exploited in diverse industrial and biomedical applications, their health hazard to humans is poorly understood. We have developed many cell models in vitro to systematically study the putative cytotoxicity [...]

Discriminated properties of PEI functionalized gold nanoparticles (Au-PEIs) predetermined by synthetic routes of ligand exchange and reduction processes: Paths and Fates

Cho T.J., Gorham J.M., Pettibone J.M., Hackley V.A., National Institute of Standards and Technology, US

Polyethyleneimine (PEI) functionalized AuNPs (Au-PEIs) have potential use as positively charged gold nanoparticles (AuNPs) for nano-medicinal applications, due to their cationic surfaces that promote cellular uptake and gene transfection.1-6 Au-PEIs can be prepared by one [...]

Accelerated Neutral Atom Beam processing of medical devices enhances tissue integration while reducing bacterial attachment

Khoury J., Phok B., Kirkpatrick S., Walsh M., Shashkov D., Exogenesis Corp, US

Accelerated Neutral Atom Beam (ANAB) technology is a low energy accelerated particle beam gaining acceptance as a tool for nano-scale surface modification of implantable medical devices. ANAB is created by acceleration of 2. METHODS neutral [...]

Remote control of mechano-sensory function of primary cilia by Fe2O3 nanoparticles in ciliopathic animal models

Pala R., Nauli S.M., Chapman University and University of California Irvine, US

In the present studies, we designed a cilia-targeted delivery system to deliver fenoldopam (FD) specifically to the primary cilia. Hence, we devised the iron oxide nanoparticle (Fe2O3-NP)-based technology for ciliotherapy. Dynamic light scattering measurements showed [...]

Bacteria Inhibitory Action of Peptides P753 and P359 in 2D and 3D Cell Cultures

Masuda J., Vig K., University of Hawaii at Manoa, US

The current study investigated two proprietary peptides, p359 and p753, for their antibacterial activity against Escherichia coli (E.Coli) and Staphylococcus aureus (S. aureus). Minimum Inhibitory Concentration (MIC) of bacteria for p359 and p753 was 50μg/mL [...]

Large-Area Micro and Nanopatterned Drum Molds through Novel Nanocoining Process

Furst S., Miller N., Smart Material Solutions, Inc., US

Nanostructured surfaces have unique optical and wetting properties that can transform commercial products including OLEDs, biosensors, wire-grid polarizers, solar panels, and augmented and virtual reality headsets. Still, nanopatterning is generally limited to small-area, high-cost applications [...]

Wearable IoT Devices for Health Monitoring

Bhat G., Tuncel Y., An S., Ogras U.Y., Arizona State University, US

Advances in wearable electronics pave the way for a new class of devices that combine sensing, process- ing, and communication. These devices enable a wide range of applications including health monitoring, ac- tivity tracking, and [...]

Chemical-Free Metal PDMS Thermal Bonding in Flexible Bio-Potential Electrode Fabrication

Koh D., Wang A., Oh K.W., University at Buffalo, US

The flexible bio-potential electrode is gaining signifiacnt interest in wearable or implantable biosensors. Among many soft materials, polydimethylsiloxane (PDMS) is widely studied because of its good biocompatibility and elasticity. However, due to the nature of [...]

Resistive Pressure Sensor with Carbon Nanotube Electrodes towards Flexible Electronics Applications

Palumbo A., Zhang R., Yan K., Yang E.H., Chen S., Hader G., Chang J., Yang E.H., Stevens Institute of Technology, US

Here, we present a flexible and stretchable pressure sensor composed of vertically aligned CNTs (VACNTs) partially embedded in a polydimethylsiloxane (PDMS) substrate. VACNTs were grown via chemical vapor deposition and transferred onto PDMS as a [...]