US – Page 10 – TechConnect Briefs

Multilayer Low Tg Inorganic Glass/Polymer Barrier Films

Vennerberg D., Bemis Company, Inc., US

Conventional high barrier films are produced by coating or laminating inorganic materials to polymeric substrates. While successful at lowering the permeability of the films, several unit operations are required to introduce multiple inorganic barrier layers. [...]

Vitamins C and B1: Amorphization, Crystallization, and Vitamin Degradation

Mauer L.J., Ismail Y., Arioglu-Tuncil S., Voelker A.L., Purdue University, US

Crystalline ingredient forms of water soluble essential vitamins C and B1 may dissolve or melt during food production, and then re-solidify in crystalline or amorphous forms. This study compared the phase transformations, amorphization, and chemical [...]

Yeast Cell Wall Particle Encapsulation of Pro-Terpene Payloads

Soto E., Rus F., Ostroff G., University of Massachusetts Medical School, US

Terpenes are naturally occurring compounds produced by plants that have long been recognized for their insecticidal, antimicrobial, and antioxidant properties. However, applications of terpenes have been limited by their volatility and poor water solubility resulting [...]

An ultrasensitive and culture-free detection platform for microorganisms and protein biomarkers

Yau S.-T., Rapidect, Inc., US

We have developed an electrochemical immunoassay platform, which detects a range of disease-related targets including bacteria, viruses, fungi and protein biomarkers. The platform features a voltage-controlled signal amplification, which leads to ultrasensitive detection. The analytical [...]

Catalytic Nanoparticles to Enhance the Sensitivity of Lateral Flow Immunoassays

Kidwell D.A., Wei E., Lanese J.N., Mulvaney S., Naval Research Laboratory, US

Lateral-flow immunoassays (LFIAs) are a widely used point- of-care technology. They are most familiar as home-pregnancy tests, but are also employed for testing for a wide variety of diseases, biomarkers, and even small molecules. By [...]

Nanobiomimetic Structured Organo-Metal Devices Direct Rapid Real-time Monitor Atto Molarities of ATP in Biological Specimens

Chen E.T., Thornton J.T., Duh S-H, Kissinger P.T., Advanced Biomimetic Sensors, Inc., US

Real-time monitoring of ATP in biological specimens is a convenient means to monitor the hygiene in healthcare units and for medical devices. Rapid and precise monitoring of ATP has been in strong demand. We report [...]

Air Powered Artifical Lungs and other High Efficiency Fluid Reactor Innovations

Strobl K., Gainey S., Kumar A., Kumar A., CVD Equipment Corporation, US

Commercially available Hollow Fiber (HF) based Extracorporeal Membrane Oxygenators (ECMO) are presently being built using a parallel assembly of over 10- 20K of porous hollow polymeric fibers as respective reactor core elements (RCE). They are [...]

A Biomedical Sensor Based on Resonant Absorption of Ultrasound Waves in Hydrogel-based Resonators

Farhoudi N., Leu H-Y, Magda J., Solzbacher F., Reiche C.F., University of Utah, US

Smart hydrogels can be tailored to undergo a vol- ume change in response to an analyte. The potential biocompatibility of these materials has made them a very promising material for biomedical sensing applica- tions. To [...]

M2D2: a successful model catalyzing medical device innovation and development

Hafer N., McManus D., Picard M., Tello, S., University of Massachusetts Center for Clinical and Translational Science, US

The Massachusetts Medical Device Development (M2D2) center offers inventors and small medical device companies coordinated access to research, engineering, and clinical investigation at the UMass Medical School (UMMS) and UMass Lowell (UML) campuses. UMMS provides [...]

Personalized nanomedicine for the treatment of vascular hypertension in polycystic kidney disease models

Pala R., Nauli S.M., University of California Irvine, US

In our current study, we designed a nanomedical device for the treatment of vascular hypertension in polycystic kidney disease (PKD) model through cilia targeting. We generated and compared two different metal and polymer cilia-targeted nanoparticle [...]