RU – Page 7 – TechConnect Briefs

Control of NEMS Based on Carbon Nanotube

Ershova O.V., Knizhnik A.A., Lebedeva I.V., Lozovik Yu.E., Popov A.M., Potapkin B.V., Kintech Lab Ltd, RU

Here we consider the controlled operation of a gigahertz oscillator based on a carbon nanotube. A new method for controlling the motion of nanoelectromechanical systems (NEMS) is proposed. This method is based on the appearance [...]

The IMPRINT software: quantitative prediction of process parameters for successful nanoimprint lithography

Kehagias N., Reboud V., Sotomayor Torres C.M., Sirotkin V., Svintsov A., Zaitsev S., IMT RAS, RU

A homogeneous residual layer thickness in nanoimprint lithography (NIL) can be achieved by optimizing the NIL stamp geometry (the distribution of cavities and protrusions, the stamp cavities depth and the stamp thickness) as well as [...]

Influence of Nanoparticles on the Nervous Tissue Properties

Reshetov I.V., Chissov V.I., Sukharev S.S., Timoshenko V.Y., Sidletskiy V.Y., Forsh P.A., P.A.Hertzen Moscow Research Oncological Institute, RU

Interaction between the nanoparticles and nervous tissue in the process of the damage healing is the object of study in the present work. Laboratory animal (rat) was put into deep narcosis. The Nervus ischiadicus was [...]

Pharmacokinetic study of PEGylated plasmon resonant gold nanoparticles in tumor-bearing mice

Kogan B.Ya., Andronova N.V., Khlebtsov B.N., Khlebtsov N.G., Khlebtsov B.N., Khlebtsov N.G., Rudoy V.M., Dement’eva O.V., Sedykh E.M., Bannykh L.N., FGUP “GNC “NIOPIK”, RU

Gold nanorods and gold nanoshells have been synthesized. Nanorods have length of 50 nm, diameter of 15-20 nm. Nanoshells have 80 nm silica core diameter with 25 nm thick gold shells. Then poly(ethylene glycol) molecules [...]

Preparation and investigation of biological activity of thermosensitive liposomes loaded with doxorubicin

Tazina E.V., Polozkova A.V., Orlova O.L., Ignatieva E.V., Mescherikova V.V., Wainson A., Yarmonenko S.P., Oborotova N.A., N.N.Blokhin Russian Cancer Research Center of RAMS, RU

Purpose: Preparation of thermoliposomes with doxorubicin and investigation of their effect on solid Ehrlich carcinoma and B-16 mouse melanoma in combination with hyperthermia. Materials and methods: Thermosensitive liposomes were prepared using DPPC, DSPC, DSPE-PEG 2000 [...]

Influence of liposome size on accumulation in tumor and therapeutic efficiency of liposomal near-IR photosensitizer for PDT based on aluminum hydroxide tetra-3-phenylthiophthalocyanine

Meerovich G.A., Meerovich I.G., Meerovich G.A., Meerovich I.G., Pevgov V.G., Lukyanets E.A., Oborotova N.A., Gurevich D.G., Zorin A.A., Derkacheva V.M., Smirnova Z.S., Loschenov V.B., Vorozhtsov G.N., Baryshnikov A.Yu., A.M. Prokhorov General Physics Institute of RAS, RU

Size of nanoparticles is considered to be the one of main factors determining the efficiency of nanostructural antitumor drugs. Current work was performed to estimate the influence of liposomal size distribution on level and selectivity [...]

New efficient nanostructural near-IR photosensitizer for photodynamic therapy of malignancies based on micellar dispersion of zinc octa-4,5-decylthio-3,6-chloro-phthalocyanine

Meerovich G.A., Meerovich I.G., Meerovich G.A., Meerovich I.G., Lukyanets E.A., Negrimovsky V.M., Barkanova S.V., Zorin A.A., Umnova L.V., Oborotova N.A., Loschenov V.B., Vorozhtsov G.N., Baryshnikov A.Yu., N.N.Blokhin Russian Cancer Research Center of RAMS, RU

The work is devoted to investigation of new nanostructural photosensitizer on a base of zinc octa-4,5-decylthio-3,6-chloro-phthalocyanine solubilized in micellar dispersion. Photosensitizer possesses its absorption maximum at about 730 nm and can be considered promising for [...]

Biochip-Based Test System for Cancer Diagnostics. Simultaneous Quantitation of Total and Free Forms of Prostate-Specific Antigen

Osipova T., Sokolova Z., Ryabykh T., Karaseva V., Modorsky M., Matveev V., Baryshnikov A., N.N. Blokhin Cancer Research Center, RAMS, RU

Background. Prostate-specific antigen (PSA) is the most useful marker for the early detection of prostate cancer (PCa). The use of two PSA forms – total (PSAt) and free (PSAf) makes it possible to differentiate benign [...]

Thin NIL films characterization (viscosity, adhesion) with rheological nano–probe

Svintsov A.A., Trofimov O.V., Zaitsev S.I., IMT RAS, RU

Polymers of different kinds are widely used in NanoImprint Lithography. First of all it is a usage of thermoplasts in thermal NIL. In step and flash imprint lithography photo-cured polymers are used. Thermocurable polymers could [...]

UV-NIL with optimal droplets

Sirotkin V., Svintsov A., Zaitsev S., IMT RAS, RU

A homogeneous residual layer thickness in nanoimprint lithography (NIL) is a serious problem in step and flash (UV-)NIL. Improvement of thickness homogeneity could be expected from optimized size of droplets at resist dispensing in case [...]