Lukyanets E.A. – TechConnect Briefs

Influence of liposome size on accumulation in tumor and therapeutic efficiency of liposomal near-IR photosensitizer for PDT based on aluminum hydroxide tetra-3-phenylthiophthalocyanine

Meerovich G.A., Meerovich I.G., Meerovich G.A., Meerovich I.G., Pevgov V.G., Lukyanets E.A., Oborotova N.A., Gurevich D.G., Zorin A.A., Derkacheva V.M., Smirnova Z.S., Loschenov V.B., Vorozhtsov G.N., Baryshnikov A.Yu., A.M. Prokhorov General Physics Institute of RAS, RU

Size of nanoparticles is considered to be the one of main factors determining the efficiency of nanostructural antitumor drugs. Current work was performed to estimate the influence of liposomal size distribution on level and selectivity [...]

New efficient nanostructural near-IR photosensitizer for photodynamic therapy of malignancies based on micellar dispersion of zinc octa-4,5-decylthio-3,6-chloro-phthalocyanine

Meerovich G.A., Meerovich I.G., Meerovich G.A., Meerovich I.G., Lukyanets E.A., Negrimovsky V.M., Barkanova S.V., Zorin A.A., Umnova L.V., Oborotova N.A., Loschenov V.B., Vorozhtsov G.N., Baryshnikov A.Yu., N.N.Blokhin Russian Cancer Research Center of RAMS, RU

The work is devoted to investigation of new nanostructural photosensitizer on a base of zinc octa-4,5-decylthio-3,6-chloro-phthalocyanine solubilized in micellar dispersion. Photosensitizer possesses its absorption maximum at about 730 nm and can be considered promising for [...]