Papers – Page 15 – TechConnect Briefs

The Automation of Protein Crystal Presentation for X Ray Diffraction Experiments using Standing Acoustic Waves in a Microfluidic Chip Environment

Burton C., Docker P., Prince M., Leaper M., Kay J., Stuart D., Evans G., Diamond light Source, UK

As the pressure continues to grow on Diamond and the world’s synchrotrons for higher throughput of diffraction experiments, new and novel techniques are required for presenting these micron dimension crystals to the X ray beam. [...]

Recent advances in capillary microflows for point-of-care and home-care devices

Berthier J., Gosselin D., Huet M., Cubizolles M., Delapierre G., CEA/LETI/MINATEC, FR

Biotechnology has been recently seeing fundamental evolutions: first, a clear shift towards biological applications; second a trend towards the design and fabrication of portable devices; third the choice of inexpensive materials such as plastic or [...]

Nephrotoxicity of Dextran Functionalized Graphene Nanoparticles and Their Potential as Magnetic Imaging Contrast Agents for Renal Abnormalities

Lee S., Kanakia S., Toussaint J., Kukarni P., Chowdhury S.M., Khan S., Shroyer K., Moore W., Sitharaman B., Stony Brook University, US

Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial and venous imaging and improve the sensitivity in detecting small [...]

Substrate addition and matrix optimization increased sensitivity and selectivity of the PLGA sensor, resulting in a stronger detection signal toward bacterial contaminations

Ibrisimovic M., Ibrisimovic N., Ibrisimovic M., Ibrisimovic N., Kesic A., Mehmedinovic M., Ibrisimovic M., Ibrisimovic N., Faculty of Science, University of Tuzla, BA

The aim of this work was to contribute to the development of a simple and cheap biomimetic sensor, providing a higher sensitivity and selectivity toward microbiological contaminations. An optimization of the matrix of the optical [...]

High-sensitive, direct and label-free detection technique of nanotoxic material using QCM

Jang K., You J., Park C., Park J., Park C., Park J., Na S., Korea university, KR

For the several decades, various nanomaterials are broadly used in industrial fields, research areas and commercialized products. Among many nanomaterials, silver ion, carbon nanotube, ZnO, and mercury ion etc are of the widely used nanomaterial [...]

In Situ Health Monitoring of Piezoelectric Sensors

Jensen S.L., NASA - Stennis Space Center, US

The technology developed is an in-situ measurement system for monitoring the performance of piezoelectronic sensors, particularly accelerometers. With this technology, characteristics such as resonant frequency, response, cable status, connectivity, bonding and linear range, can be [...]

A Nanobiomimetic Neuronal Memcapacitor Serves as a Voltage Sensor and an Amperometry Sensor for Reagent-less Direct Detection of Sub pM Soluble Amyloid-beta

Duh S-H, Thornton J., Kissinger P.T., Chen E.T., Advanced Biomimetic Sensors, Inc., US

Amyloid-beta (A) plaque accumulation in the brain has been recognized to be associated with Alzheimer’s and dementia. Challenges of quantitation of Ab are the instability of soluble Ab1-42 and the protein interference plus the time [...]

Multilayer optical strip for illumination, imaging and analysis

Gomez-Gonzalez E., Marquez-Rivas J., Perales-Esteve M.A., Mayorga-Buiza M.J., University of Seville, ES

An optical device (multilayer optical strip, MOS) is presented. It is composed of a small-sized, strip-shaped, multilayer, planar structure connected to a control unit. Active and passive optical elements allow for controlling the properties, spatial [...]

Enhanced Kinetics of Enzymatic Nanosensors

Breger J., Walper S., Ancona M., Stewart M., Susumu K., Medintz I., Naval Research Laboratory, US

Nanosensors employing quantum dots (QDs) and functional moieties such as enzymes are promising for diagnostics and chemical/biological threat activity. Their small size permits cell penetration and their inherent photochemical properties are well-suited for rapid, optical [...]

Beyond Biomarkers: Array-Based Profiling for Diagnostics and High-Throughput Screening

Rotello V., University of Massachusetts Amherst, US

The "chemical nose/tongue" approach presents a potential alternative to specific recognition and separations techniques. In this approach a sensor array is generated to provide differential interaction with analytes via selective receptors, generating a stimulus response [...]