Papers – Page 31 – TechConnect Briefs

An Integrated Microfluidic Real-Time PCR System for Pathogen Detection

Zhu L., Li L., Li Z., Lin F., Liu Y., An D., Wang M., Wang Y.K., Zhang G., Zhang L., Wang M., Wang Y.K., Li L., Li Z., Lin F., Liu Y., Liu Y., Zhang G., Zhang L., Lin F., University of Manitoba, CA

The development of microfluidics-based PCR for rapid genetic analysis particularly pathogen detection is an emerging research field. Recent advancement of microfluidics critically enabled the development of various on-chip PCR systems to realize its apparent advantages [...]

DNA detection using Laser Transmission Spectroscopy

Li F., Mahon A.R., Barnes M.A., Egan S., Feder J., Lodge D.M., Hwang C.-T., Schafer R., Ruggiero S.T., Tanner C.E., University of Notre Dame, US

Laser transmission spectroscopy (LTS) is a new quantitative and rapid technique for measuring the size, shape, and number of nanoparticles in suspension. We report on the application of LTS as a novel detection method for [...]

CarouCELL – a novel compact submerged perfusion bioreactor for drug screening and tissue engineering

Foss M., Le D.Q.S., Aarhus University, DK

Development of traditional methods of cell growth and manipulation on 2-dimensional (2D) surfaces, have been shown to be far from optimal for new challenges of tissue engineering and drug screening. This has lead to the [...]

Continuous Sensing of blood by dark-field microscopy and surface-enhanced Raman Spectroscopy

Henry A.-I., Sharma B., Sagle L.B., Van Duyne R.P., Northwestern University, US

Surface-enhanced Raman spectroscopy (SERS) is a rapid, label-free technique with multiplexing capabilities, making it very relevant for the sensitive real-time detection for biomedical applications , , . Demonstration of in vivo glucose detection with unprecedented [...]

Encapsulation of nanoparticles with multifunctional, cross-linkable diblock copolymers for biomedicine

Schmidtke C., Ostermann J., Tran H., Pöselt E., Kloust H., Niehaus J., Becker S., Kreuziger A., Werner K., Pietsch A., Weller H., University of Hamburg, DE

We would like to present a micellular encapsulation method for nanoparticles (quantum dots, iron oxides, gold) which is based on a ligand exchange procedure of native ligands with a prepolymer poly(isoprene)-diethylentriamine (PI-N3) and subsequent ligand [...]

Magneto-plasmonic Nanoplatforms for Enhanced Bioimaging and Photothermal Cancer Therapy

Kopwitthaya A., Ohulchanskyy T.Y., Jeon M., Law W-C., Xie Q., Chada R.R., Xue X., Furlani E.P., Kim C., Prasad P.N., University at Buffalo (SUNY), US

Multifunctional nanoplatforms are finding increasing use in a host of emerging applications in the fields of biophotonics and nanomedicine where they are used to target, probe, image and treat tissue at the cellular and subcellular [...]

A Metallofullerene Nanoparticle Platform for Imaging and Treatment of Glioblastoma Multiforme Tumors

Dorn H.C., Zhang J., Fatouros P., Shultz M.D., Wilson J.D., Virginia Polytechnic Institute and State University, US

Glioblastoma multiforme (GBM) brain tumors occur as masses with infiltrative margins that are extremely invasive. GBMs result in a high recurrence rate with a poor prognosis for patients who are newly diagnosed with only an [...]

A sensing properties study on miniature Au/SnO2 gas sensor for hydrogen sulfide detection

Chang B-W, Ding S-J, Chen R.L.C., Hungkuang University, TW

The purpose of this study was to investigate the sensing properties for self-developed hydrogen sulfide gas sensor. In different temperature treatment and Au nano-particles doping ration, the sensitivity and selectivity of Au/SnO2 gas sensor were [...]

Sample Preparation by On-Chip Dielectrophoretic Separation and Concentration of Viable, Non-Viable and Viable but Not Culturable (VBNC) Escherichia coli

Packard M., Shusteff M., Alocilja E., Michigan State University, US

Although bacterial culture remains the gold standard for detection of viable bacteria in environmental specimens, the typical time requirement of twenty-four hours can delay and even jeopardize appropriate determination. In addition, culture is incapable of [...]

Ultralow Detection of Bio-markers using Gold Nanoshells

Patel D., Zhang G., Sun X., Gobin A.M., Keynton R.S., University of Louisville, US

The focus of this project is to improve the detection of antigen/biomarkers/viral vectors using gold nanoshells (GNS). The assay used in this project is based on aggregation of GNS in presence of antigen or viral [...]