Papers – Page 29 – TechConnect Briefs

Triple protection delivery system for retinaldehyde: Preparation, skin penetration and controlled release at the hair follicles

Supmuang P., Wanichwecharungruang S., Chulalongkorn University, TH

Vitamin A and its derivatives including retinaldehyde possess serious instability problem. To continuously supply skin with un-degraded retinaldehyde, nanoparticles which could penetrate into skin via hair follicles and then slowly release this vitamin A derivative [...]

Electrically-Controlled Drug Release System to Assist Wound Healing

Zhu S., Mbugua J., Chase M., Maskrod J., Jung J.H., Nicholson III T., Fabrizio E., Mercado R., Crosslink, US

The localized, controlled delivery of therapeutic agents is an attractive prospect for drugs with detrimental systemic effects at large dosages. An electronically-controlled drug delivery system (DDS) for the controlled release of negatively charged model compounds [...]

Novel Organofunctional Silane Coatings on Silica-Coated Ti

Matinlinna J.P., Tsoi J.K.H., The University of Hong Kong, HK

This in vitro study characterizes a developed novel silane system method to produce coatings on Ti. Hydrophobic coatings are needed in prosthetic dentistry to promote durable adhesion between luting resin cements and coated Ti surfaces. [...]

Hyaluronan-modified Magnetic Hydroxyapatite Nanoparticles for Hyperthermia

Wu H.C., Hsieh S.-Y., Wang T.-W., Tatung University, TW

The success of tumor therapy is determined by the efficiency with which the killing of tumor cells is achieved under conditions of no or only slight damage to the normal tissues. Because of its high [...]

Novel smart bio-nanomaterials: bioactive glasses containing metal nano-particles conjugated with molecules of biological interests

Malavasi G., Lusvardi G., Menabue L., Ferrari E., Saladini M., Aina V., Martra G., Bergandi L., Ghigo D., University of Modena and Reggio Emilia, IT

Stimuli-responsive materials (smart materials) hold great promises for social and economic development and are of great relevance in both fundamental research and technological applications. Their design and realization through innovative processes involve complementary expertises, with [...]

Nanoscale SPM Characterisation of Nacre Argonite Plates and Synthetic Human Amyloid Fibres

Grishin I., Tinker C., Allsop D., Robson A., Kolosov O.V., Lancaster University, UK

Nacre exhibits structural robustness despite the brittle nature of its constituents. A detailed understanding of its fabrication principles developed in nature can lead to new ideas in material design and synthesis. But due to this [...]

Bicelles: New Lipid Nanosystems for Biomedical Applications

Barbosa-Barros L., Rodriguez G., Rubio L., Cocera M., Alonso C., de la Maza A., Lopez O., Inst. Advan. Chemistry Catalonia-CSIC, ES

Bicellar nanosystems are a fascinating category of morphologically adaptable and versatile lipid assemblies consisting in bilayered disk-shaped nanoaggregates formed in water by long and short alkyl chain phospholipids. Characteristics of these bicellar systems, such as [...]

Mechanical Characterization of Prion Fibrils using Coarse-grained Modeling Approach in Silico

Yoon G., Kim Y.K., Eom K., Na S., Korea university, KR

Recently, prion is aroused interest with amyloid for its fatality in human and animal`s disease such as Creutzfeldt–Jakob disease and bovine spongiform encephalopathy. The prion has nanoscale long fibrillar form and exists high mechanical properties, [...]

Fabrication of Microelectrodes on Polyester Membranes for Dielectrophoretic Cell Capture

Hanke C., Dittrich P.S., Reyes D.R., National Institute of Standards and Technology, US

We present a new system for cell capturing on porous polyester (PET) membranes using dielectrophoretic forces. For the first time gold microelectrodes were fabricated on PET membranes using conventional photolithographic techniques. Their characterization revealed no [...]

Aerosol based fabrication of thiol-capped gold nanoparticles and their application for gene transfection

Byeon J.H., Roberts J.T., Purdue University, US

Thiol-capped Au nanoparticles can be used as sensitive probes of gas and vapor concentrations, as magnetic materials in data storage devices, for selective drug delivery, and for biomedical imaging.3 In this study, ambient-spark-produced-Au-nanoparticle-laden nitrogen gas [...]