Papers – Page 23 – TechConnect Briefs

Transport of Nanomaterials in Complex Media

Ubaque L.A., Vargas W.L., Universidad de los Andes, CO

An appreciable number of researchers have analyzed both the genotoxicity and cytotoxicity of nanoparticles in biological systems, noting extensive damage to most body organs, such effects are attributed to: i) the ease of transportation to [...]

A Regulator’s Approach to Nanomaterials

Takatori S., Wong J., California Environmental Protection Agency (Cal/EPA), US

Policymakers and regulators appear to have a mistaken belief that a singular overarching definition of “engineered nanomaterials” is a requirement for any possible regulatory strategy. Previous attempts, most recently by the European Commission, have shown [...]

Characterization of a Vortex Shaking Method for Producing Airborne Glass Fibers for Toxicology Studies

Ku B.K., Deye G., Turkevich L.A., National Institute for Occupational Safety and Health (NIOSH), US

Current fiber measurement techniques arose primarily due to health concerns over asbestos exposure. Fiber toxicity appears to be mostly a function of fiber concentration, dimensions (diameter and length) and durability in the lungs. A fiber [...]

Cancer cell targeting of lipid gene vectors by protein corona

Caracciolo G., Pozzi D., Capriotti A.L., Cavaliere C., Cardarelli F., Bifone A., Laganà A., Sapienza University of Rome, IT

We investigated the compositional evolution of the protein corona of 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) cationic liposomes (CLs) that efficiently deliver DNA in a wide variety of cell lines as a function of increasing human plasma (HP) [...]

Fungicidal nanoparticles of low toxicity from cationic lipid and polyelectrolytes

Melo L.D., Carmona-Ribeiro A.M., Universidade de Sao Paulo, BR

The assembly of the cationic lipid dioctadecyldimethylammonium bromide (DODAB) and polyelectrolytes such as carboxymethylcellulose (CMC) and polydiallyldimethylammonium chloride (PDDA) produced bactericidal nanoparticles in complete absence of antibiotics. In this work, these nanoparticles are evaluated regarding [...]

Cytotoxic Effects of Four Metallic Oxide Nanoparticles on Dorsal Root Ganglion (DRG) Neurons

Lu S., Bhushan A., Leung S.W., Daniels C.K., Lai J.C.K., Idaho State University, US

Metallic oxide nanoparticles have diverse industrial applications because of their exploitable physico-chemical and other properties. Consequently, the occupational environmental exposure of humans to these nanparticles is increasing; however, the health impact of their exposure has [...]

Cytotoxicity of Magnesium Oxide Nanoparticles in Schwann Cells

Idikuda V.K., Jaiswal A.R., Wong Y.Y.W., Bhushan A., Leung S.W., Lai J.C.K., Idaho State University, US

Diverse applications of metal oxide nanoparticles in various industries have been accelerating in the last decade. Magnesium oxide (MgO) nanoparticles have been employed in ceramics, and as adhesive and additive in chemical raw materials, leading [...]

Cytotoxic Effects of Short Multi-Wall Carbon Nanotubes in Dorsal Root Ganglion (DRG) Neurons

Lai J.C.K., Gao W., Bhushan A., Leung S.W., Idaho State University College of Pharmacy, US

Because of their unique physico-chemical properties, carbon nanotubes (CNTs) have found their way into diverse industrial and biomedical applications. Their escalating uses in multiple industries result in enhanced occupational human exposure to CNTs. However, the [...]

Evaluating safety and stability of CNT nanocomposites exposed to environmental conditions

Orlov A., Ramakrishnan G., Ging J., Hubert A., Feka P., Korach C.S., Stony Brook University, US

There is a growing interest in the development of nanocomposites consisting of organic polymers and various nanomaterials. These materials can provide unique functionalities as compared to unmodified polymers in terms of dielectric behavior, thermal and [...]

Evidence for a direct interaction between poly-dispersed single-wall carbon nanotubes and murine erythrocytes resulting in in vitro and in vivo cytotoxicity

Sachar S., Saxena R.K., Jawaharlal Nehru University, IN

Single wall Carbon Nanotubes (SWCNTs) are highly hydrophobic in nature and agglomerate strongly. Treatment of SWCNTs with sulphuric and nitric acid (acid functionalization) results in the introduction of carboxy and sulfonate groups on SWCNTs and [...]