Papers – Page 27 – TechConnect Briefs

A Behavior of Protein Adsorption on Poly(Ethylene Glycol)-Modified Surfaces under Flow Conditions at Relatively Low Concentrations for Microfluidics Systems

Chun C-J, Lenghaus K., Riedel L., Bhalkikar A., Hickman J.J., University of Central Florida, US

Microfabrication technology has been used to create new microfluidics systems for bioanalytical and medical device applications in the last decade. The handling of relatively small amounts of analytes, at significantly lower concentrations, combined with the [...]

Characterisation of thin film piezoelectric materials by differential interferometric techniques

Cain M.G., Steward M., Downs M., National Physical Laboratory, UK

Piezoelectric thin films are considered emergent materials for integration within Micro Systems Technology (MST) or MEMS devices. The development of suitable measurement facilities to characterise the materials functional properties is complicated by the fact that [...]

Optical and impedance detection of DNA hybridisation on barcoded micro particles in a microfluidic device

Holmes D., Whitton A., Cavalli-Petraglia G., Galitonov G., Birtwell S., Banu S., Zheludev N., Morgan H., University of Southampton, UK

A common problem with high throughput combinatorial chemistry is the inability to easily analyse and track the multitude of molecules produced. This bottleneck is a major problem for the big pharmaceutical companies and other researchers [...]

Modeling multi-scale liquid dispersion phenomena in conjunction with Computational Fluid Dynamics

Mohan S., Haidari A., Mukopadhyay A., Fluent, Inc., US

Mixing of fluid in different geometric scales dominates variety of real life applications ranging from engineering chemicals, food materials, pharmaceutical products to biological organs. In this presentation we will address coupling of continuum scales in [...]

Cell and Particle Concentration on the Chip

Irimia D., Toner M., Massachusetts General Hospital, Harvard Medical School, US

Lab-on-a-chip devices for cell processing and analysis are increasingly sophisticated and targeting a wider spectrum of scientific research and clinical diagnostic applications. Despite recent advances however, many sample preparation steps, common for macro-scale techniques, have [...]

Thermal modeling of a PMMA microfluidic separation chip

Zhu Y., Bui A., CSIRO Australia, AU

The main objective of the current work is to investigate the thermal performance, in particular Joule heating of polymer microfluidic chips involving electrokinetically driven flows using experimental and numerical methods. Most of the work focused [...]

Microfluidic T-Form Mixer Utilizing Pressure Disturbances

Ma Y.B., Fields M., Sun C.P., Zhang F.Y., Liao J-C, Li Y., Liao J-C, Churchill B.M., Ho C-M., University of California at Los Angeles, US

A simple solution to mixing problems in micro fluidic systems was presented in this paper. A T-form microfluidic mixer was designed and tested utilizing pressure disturbances. The performance of the mixer was studied through both [...]

Chaotic flows in microchannels: A lattice Boltzmann study

Varnik F., Raabe D., Max-Planck Institut fuer Eisenforschung, DE

Lubricant flows are usually assumed to be laminar and the lubricatedmetallic surfaces are anticipated to be perfectly flat and references therein). Both assumptions are incorrectwhen it comes to a detailed analysis. Indeed, metallic surfaces arenever [...]

Chemically Robust Microfluidic Devices for Radiochemistry Platforms

Rolland J.P., Elizarov A., Brewster J., Heath J.R., DeSimone J.M., Liquidia Technologies, US

We report the fabrication of solvent-compatible microfluidic devices based on photocurable “Liquid Teflon” materials. The materials are highly fluorinated functionalized perfluoropolyethers (PFPEs) that have liquidlike viscosities that can be cured into highly durable elastomers that [...]

A Micromachined Sparse Cell Isolation Device: Application in Prenatal Diagnostics

Mohamed H., Turner J.N., Caggana M., Wadsworth Center, New York State Department of Health, US

The isolation of fetal cells from maternal circulation is the subject of intense research. Fetal cells can be isolated using several enrichment methods, however no technique to specifically isolate and use them for genetic diagnosis [...]