Micro & Bio Fluidics, Lab-on-Chip – Page 9

Capture of circulating tumor cells (CTCs) using a novel micro-device

Ranjan S., Yong Z., National University of Singapore, SG

Circulating tumor cells (CTCs) are metastatic cells that are detached from a tumor and are found in the blood of cancer patients. The presence of CTCs in the blood indicates the metastatic stage of cancer, [...]

Scalable gas phase nanoparticle treatment methods required for large-scale nanofluid and nanocomposite synthesis

Dion C.A.D., Tavares J.R., École Polytechnique de Montréal, CA

Recent work has demonstrated that while nanofluids do indeed exhibit increased heat transfer properties , there is no abnormal enhancement as had been claimed by early proponents of nanofluids. However, this lack of abnormal enhancement [...]

A Novel Compact Lab-on-a-Chip Nanosensor for In-Channel Liquid Viscosity Detection

Zhao J., Xu J., Xue W., Xue W., Washington State University Vancouver, US

Real-time monitoring of liquid’s viscosity has significant impacts on many areas such as medicine, biology and petrochemistry. However, most existing sensors have complicated fabrication and testing processes and are not truly compatible with fluidic systems [...]

Single-cell manipulation using Nanopipettes

Maalouf M.M., Jain M., Actis P., Pourmand N., University of California, Santa Cruz, US

Manipulation and analysis of individual cells is key in understanding processes that control single-cell behavior in complex environment. Nanotechnology-based tools having high sensitivity and low invasiveness are holding great promises as new biomedical devices for [...]

Uncoil long DNA molecules in nanoposts array

Wu J., Shao G., Choi J., Uba F.I., Soper S.A., Park S., Louisiana State Univ., US

A nanoposts array was fabricated on a PMMA based nanofluidic chip by nanoimprinting lithography. The electrophoresis of Lambda and T4 DNA in the nanoposts was studied. A periodical stretching and recoiling motion was observed. Each [...]

All-In-Polymer Injection Molded Device for Single Cell Capture Using Multilevel Silicon Master Fabrication

Tanzi S., Larsen S.T., Matteucci M., Taboryski R., Technical University of Denmark, DTU Nanotech, DK

This work demonstrates a novel all-in-polymer device for single cell capture applicable for biological recordings. The chip is injection molded and comprises a “cornered” (non planar) aperture. Zanetti et al. have reported that mammalian cells [...]

Effects of Solvents on Dissolution of Photoresist in Parylene Microchannels

Ceylan Koydemir H., Kulah H., Ozgen C., Tosun I., Middle East Technical University, TR

This paper presents a detailed study for the effects of different types of solvents on dissolution of photoresist inside the parylene micro-channels, for the first time. Experimental results indicate that photoresist dissolution in dipolar aprotic [...]

Polymer microfluidic chip with embedded CNTs for DNA sample preparation

Khuntontong P., Chan J.X., Gong M., Wang Z.P., Singapore Institute of Manufacturing Technology, SG

We present a polymer-based microfluidic chip which has deposited carbon nanotubes (CNTs) onto the microchannel. The chip is capable of performing DNA preparation process like restriction enzyme digestion and ligation of DNA. The advantage of [...]

Free-Surface Microfluidics: Exploring New Actuation and Sensing Methods

Yu G., Lei N., Chen X., Xue W., Xu J., Xue W., Washington State University, US

Unlike traditional microchannel-based microfluidics, free-surface microfluidics features no channel, ease to clean, simple design fabrication and operation, as well as external access to the samples. It has been proven that free-surface droplets can be actuated [...]

Numerical Study on a passive micromixer with sinusoidal channel walls

Afzal A., Kim K-Y, Inha University, KR

Mixing of liquid samples in microfluidic systems has attracted many researchers mainly due to small characteristic dimensions of these channels, absence of turbulence and small diffusion coefficients. Depending on the mode of operation, different realizations [...]