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HomeTopicsMicro & Bio Fluidics, Lab-on-Chip

Topic: Micro & Bio Fluidics, Lab-on-Chip

Scaling of Electroosmotic Flow and Ionic Conductivity in Nanochannels

Qiao R., Aluru N.R., Beckman Institute for Advanced Science and Technology, US
Electrokinetic transport is widely encountered in many nanofluidic systems, and understanding its scaling as a function of various operating conditions, e.g., bulk concentration, is important for establishing design rules and for exploring the design space. [...]

Multiscale Modeling of Nanoflows

Drazer G., Acrivos A., Khusid B., Koplik J., New Jersey Institute of Technology, US
Using molecular dynamics simulations, we identified in previous work a new adsorption phenomenon in which, for poorly wetting fluids, a suspended particle, initially moving along the center of the nanochannel, is adsorbed onto the tube [...]

Computational Analysis of On-line Coupled ITP-CE

Horner M., Fluent, Inc., US
Lab-on-a-chip technologies combine a sequence of chemical and/or biological analyses on a miniaturized platform to perform an analytical task or series of tasks. Lab-on-a-chip applications include chemical/biological agent detection, DNA sequencing/analysis, and drug discovery, to [...]

System Simulations of Complex Electrokinetic Passive Micromixers

Wang Y., Lin Q., Mukherjee T., Carnegie Mellon University, US
This paper presents a composable system simulation framework using an analog hardware description language implementing behavioral models for electrokinetic micromixers that are capable of accurately capturing the effects of mixer topology/geometry, flow ratio and material [...]

Applications of Topology Optimization in the Design of Micro- and Nanofluidic Systems

Okkels F., Olesen L.H., Bruus H., Technical University of Denmark, DK
The material distribution method in topology optimization was developed in the late 1980ies for stiffness design of mechanical structures, and only recently the first steps have been taken towards implementing the method in fluidics. Topology [...]

Flat Fluidics: Programmable On-Chip Networks for Biological and Chemical Applications

Wixforth A., University of Augsburg and Advalytix AG, DE
We present a novel approach towards the needs of a versatile microfluidic chip-based microfluidic system with unique properties and functionality. Like for microarrays and in contrast to many existing microfluidic technologies, the fluid handling is [...]

Design Paradigms and Methodologies for Microfluidics

Hardt S., Darmstadt University of Technology, DE
This paper reviews and compares different strategies for designing and building up microfluidic systems, with a special emphasis on the system aspect as opposed to single components capable of performing only special operations. An overwhelming [...]

Micro and Nano Fluidics Design and Phenomena

DEP Particle Dynamics and the Steady Drag Assumption

Wereley S.T., Whitacre I., Bashir R., Li H.B., Purdue University, US
The interaction of fluid drag, dielectrophoretic forces, and Brownian motion on a nanoparticle's motion is studied using a microfluidic chip with interdigitated electrodes. The flow domain is a 12 micron deep by 150 micron wide [...]

Novel 2D Interfaces for Nanoelectrospray-Mass Spectrometry

Arscott S., Le Gac S., Druon C., Tabourier P., Rolando C., USTL, FR
This work concerns the development, fabrication and testing of novel 2D nanoESI emitter tips. The design of the emitter tips follows a fountain pen model; fabrication relies on the use of the negative photoresist SU-8. [...]

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