Micro & Bio Fluidics, Lab-on-Chip – Page 21

‘Lab on a chip’ Label Free Protein Sensor Systems Based on Polystyrene Bead and Nanofibrous Solid Supports

Kunduru V., Prasad S., Patra P.K., Sengupta S., Portland State University, US

Polystyrene bead and electrospun polystyrene nanofibers are employed as subjects of study in this protein biomarker sensor. The study is conducted to compare the sensitivity and efficiency of the polystyrene nanofibers and microspheres as protein [...]

Study on fluorescent detection glucose molecule marked with ZnSe nano crystalline in microchannels

Bai Z-C, Qin S-J, Guizhou University, CN

Single molecule detection has been a hot point problem of science and research, classic dye fluorescent marking technology has a many defects, for example fluorescent power low, fluorescent instability , and so on. Fluorescent quantum [...]

Nanoparticles and Ultrahigh 21 tesla MRI Microimaging of Mice Brain

Sharma R., Florida State University, US

Mice brain atlas and 3D reconstructed morphology serves a great deal od real time monitoring of pharmacological properties of drugs. Iron oxide based nanoparticles paved the way to get higher resolution and contrast using MRI [...]

Characterization of DNA Transport through a Semipermeable Membrane with the Effect of Surfactants

Leung S.W., Bartolin S., Daniels C.K., Lai J.C.K., Idaho State University, US

In current advances of biotechnology, various models of introduction of DNA into cells to alter their gene expression have important biomedical and bioengineering applications. However, the molecular mechanisms underlying how DNA’s cross cell and nuclear [...]

Lateral-Driven Continuous Dielectrophoretic Separation Technology for Blood Cells suspended in a Highly Conductive Medium

Seo J., Jung J., Jung Y., Han K-H, Han S-I., Han K-H, Han S-I., Jung J., Jung Y., Bruno Frazier A., Inje University, KR

This paper presents lateral-driven continuous dielectrophoretic (DEP) microseparator for separating red and white blood cells suspended in a highly conductive dilute whole blood. The DEP microseparators enable the separation of blood cells with continuous operation [...]

A High Throughput Multi-stage, Multi-frequency Filter and Separation Device based on Carbon Dielectrophoresis

Martinez-Duarte R., Andrade-Roman J., Collado-Arredondo E., Martinez S.O., Martinez-Duarte R., Madou M., University of California Irvine, US

We present a multi-stage, multi-frequency carbon dielectrophoresis (CarbonDEP) device for high throughput filtering and separation applications in the health care and biotechnology fields. CarbonDEP refers to the use of carbon electrodes to induce DEP. Up [...]

Limitations of DNA High-frequency Anchoring and Stretching

Dalir H., Nisisako T., Endo T., Yanagida Y., Hatsuzawa T., Tokyo Institute of Technology, JP

The manipulation of molecules is a crucial prerequisite for the emerging field of molecular nanobiotechnology. This paper reports measurements that characterize the immobilization of 48 kilobase-pair lambda DNA onto lifted-off microelectrodes by high-voltage and high-frequency [...]

Micron Particles Segregation in Lower Electric Field Regions in Very Dilute Neutrally Buoyant Suspensions

Qiu Z.Y., Shen Y., Tada S., Jacqmin D., The City College of New York, US

We use a spatially periodical electrode array in a fluid chamber to generate a high gradient electric field. Neutrally buoyant poly alpha olefin particles in corn oil in the chamber are transported to the lower [...]

Modeling Magnetic Transport of Nanoparticles with Application to Magnetofection

Furlani E.P., Ng K.C., University at Buffalo, US

Magnetic nanoparticles are finding increasing use in a broad range of bioapplications, primarily as carrier particles for biomaterials such as cells, proteins, antigens and DNA. The use of biofunctional magnetic particles enables selective immobilization and [...]

Discrete Mixing of Nanoliter Drops in Microchannels

Rhee M., Burns M.A., University of Michigan, US

We present the theory, simulations and experiments for discrete drop mixing in microfluidic systems. The generalized analytical solutions have been derived and confirmed by simulations and on-chip experiments. The discrete drop mixing occurs in three [...]