Cancer Nanotechnology – Page 21

Mathematical Modeling of Chemotherapy Strategies in Vascular Tumor Growth using Nanoparticles

Mishra S., Katiyar V.K., Arora V., Indian Institute of Technology, Roorkee, IN

Throughout various fields of science and technology, a push towards the use of nanoscale technology is well underway. One area where nanoscale work is already well underway is within the field of drug delivery.In this [...]

Nano-structured Biodegradable Ceramics for the Prevention and Treatment of Bone Caner

Balasundaram G., Webster T.J., Purdue University, US

For people dying of some cancers such as breast and prostate, the spread of bone cancer is almost universal. Although current drug delivery systems have found a variety of uses in targeting certain forms of [...]

Injection of Molecules into Cells using a pH-Triggered Molecular Nanosyringe

Andreev O.A., Sandugu S., Engelman D.M., Reshetnyak Y.K., University of Rhode Island, US

We have engineered a molecular nanosyringe that enables injection of molecules into a target cell at acidic pH, but not at normal, physiological pH. The injection is driven by a water-soluble peptide, pHLIP (pH (Low) [...]

Characterization and In Vivo Biodistribution Studies with Poly(Ethylene Glycol)-Modified Thiolated Gelatin Nanoparticles

Kommareddy S., Amiji M.M., Northeastern University, US

Objective: The objective of the current study was to synthesize and modify thiolated gelatin nanoparticles with PEG chains, characterize, and evaluate their long circulating and tumor targeting potentials in vivo in a human breast cancer [...]

Rapid Detection of Multiple Myeloma using a microfluidic platform

Kaigala G., VanDjinkin J., Taylor B.J., Backhouse C.J., Pilarski L.M., University of Alberta, CA

MM has a unique molecular signature and is well suited as a model system for performing analysis on microchips. MM multiplex genetic analysis for clonotypic signatures and genetic abnormalities offers the possibility for genetic profiling [...]

Assessment of the dielectric properties of drug sensitive and resistant leukaemic cells before and after ion channel blockers using dielectrophoresis

Duncan L., Shelmerdine H., Coley H.M., Labeed F.H., University of Surrey, UK

Dielectrophoresis (DEP) is a phemomenon of induced particle motion in non-uniform electric fields. The effect is frequency dependent; by monitoring the motion of particles in AC fields and ananlysing the change in motion with frequency, [...]

Computer Model of Cancer Development

Barjis I., Barjis J., Sayar M., Barjis I., Barjis J., Amarrai W., New York City College of Technology, US

Cancer development is a very complex process. Wide range of factors could contribute to the development of cancer. Factor that can lead to the development of cancer can range from oxygen free radicals to micronutrient [...]

The Nucleolus and Cellular Stress: Analysis by Coherent Phase Microscopy

Tychinsky V.P., Kretyshev A.V., Klemyashov I.V., Reshetov I.V., Vyshenskaya T.V., Shtil A.A., P.A.Hertsen Moscow Research Oncological Institute, RU

Coherent phase microscopy is a nanoscale measurement technique, an original method of monitoring the responses to cellular stress. We demonstrate that: 1) optically dense subcellular structures, including the nuclei and nucleoli, can be clearly detected [...]

Detection of Live Breast Cancer Cells Using Carbon Nanotube Devices

Teker K., Cesarone G., Wickstrom E., Panchapakesan B., Frostburg State University, US

Development of new technologies for reliable early detection of cancer from biological fluids via minimally invasive methods is still a high priority. Cancer cells often overexpress characteristic surface receptors, which provide an opportunity for early [...]

Condensation of Therapeutic Oligodeoxynucleotides and Plasmid DNA with PPI Dendrimers and PPI-Modified Gold Nanoparticles

Chen A.M., Nair S.K., Thomas T.J., Thomas T.T., Thomas T.J., Thomas T.T., He H., Rutgers Unverisity, Newark, US

We demonstrated the formation of oligonucleotide nanoparticle in the presence of polypropylenimine dendrimers using total intensity light scattering as well as AFM and TEM. Confocal microscopic analysis showed that the nanoparticles formed with G4 and [...]