Medical & Biotech – Page 20 – TechConnect Briefs

Preparation and investigation of nano- carbonated hydroxyapatite/polymer composite spongy scaffolds for biomedical applications

Siddiqi S.A., Manzoor F., Azhar U., Jamal A., Tariq M., Anwar M.S., Saleem M., Chaudhry A.A., Rehman I.U., COMSATS Institute of Information Technology, PK

Spongy scaffolds containing nano-Carbonated Hydroxyapatite (nCHA), with composition Ca10(PO4)6-y(CO3)y(OH)2,with y=2,4, were prepared by the lyophilization method. Different polymers, natural gelatin (G), chitosan (CS) and polyvinyl alcohol (PVA), alone or in combination, were used to make [...]

One and two dimensional inorganic nanoparticles’ interactions with fibroblasts and stem cells

Rashkow J.T., Talukdar Y., Lalwani G., Sitharaman B., Stony Brook University, US

We report the effects of one and two dimensional transition metal dichalcogenide nanoparticles, tungsten disulfide nanotubes (WSNTs) and molybdenum disulfide nanoplatelets (MSNPs), on fibroblastic cell (mouse fibroblasts (NIH-3T3) and human adipose derived stem cell (MSC)) [...]

Three-Dimensional Macroporous Carbon Nanotube Scaffolds for Stem Cell Expansion and Maintenance

Lalwani G., Gopalan A., D’Agati M., Patel S., Talukdar Y., Sitharaman B., Stony Brook University, US

Expansion of stem cells and maintenance of their self-renewal capacity in vitro requires specialized robust cell culture systems. Conventional approaches consisting of animal derived matrices and cocktail of growth factors have limitations such as consistency, [...]

Bio-inspired Polydopamine Treatment and Nanosilver Formation for Antibacterial Uses

Chiu Y.-H., Li M.-C., Wu K.-M., Chung Y-C, National University of Kaohsiung, TW

In the study, we employed the mussels’ glue component—dopamine and its excellent reducing ability toward silver ions, to create a novel antibacterial effect on a facial mask surface so as not to add harmful antiseptics [...]

Microbial-mediated Au@biolayer core-shell nanoparticles: synthesis and application

Liu W.J., Jing C.Y., Chinese Academy of Science, CN

Gold nanoparticles (Au NPs) bio-synthesized through microbial activities create biocompatible and non-toxic nanomaterials that may have great applications in analysis, catalysis, and biomedicine. Herein, we demonstrated that Pantoea sp. IMH can generate Au@biolayer core-shell nanoparticles. [...]

Rapid prototyping bacterial spore hygro-actuators for soft robotics and adaptive materials

Cavusoglu A.‐H., Chen X., Tatem K., Sahin O., Columbia University, US

Over the past decade, rapid prototyping has migrated from the research and industrial labs into the homes of consumers. However, these solid models are limited in demonstrating dynamic actuation. A large range of soft materials [...]

Adsorption of Cd (II) Ions from Aqueous Solution Using Activated Carbon Prepared from Vitellaria paradoxa Shell

Adebayo G.B., Adekola F.A., Jimoh A.A., Alao F.O., Adegoke H.I., University of Ilorin, NG

Activated carbon prepared from vitellaria paradoxa shell using ortho-phosphoric acid as activating agent was used for the removal of Cd (II) ions from aqueous solution. The adsorbent sample was characterized by some physicochemical and spectroscopic [...]

Bioabsorbable Anti-inflammatory Material: A Novel Protein-Conjugated Polymer with Applications in the Implantable Medical Device Field

Rapier C.E., Chen E., Liu W.F., Lee A.P., University of California Irvine, US

Biodegradable/bioabsorbable materials are a relatively new movement in the implantable medical device field. Despite the promise of non-permanent implants, bioabsorbable materials can induce a localized inflammatory immune response. To overcome this limitation, we are combining [...]

Biomaterials

Nephrotoxicity of Dextran Functionalized Graphene Nanoparticles and Their Potential as Magnetic Imaging Contrast Agents for Renal Abnormalities

Lee S., Kanakia S., Toussaint J., Kukarni P., Chowdhury S.M., Khan S., Shroyer K., Moore W., Sitharaman B., Stony Brook University, US

Contrast-enhanced magnetic resonance angiography (MRA) employs the use of blood pool contrast agents (CA) such as gadolinium (Gd3+) complexes that allow for delayed phase arterial and venous imaging and improve the sensitivity in detecting small [...]