Medical & Biotech – Page 153 – TechConnect Briefs

Simulation Toolkit for Micro-Fluidic Pumps using Lumped Models

Litterst C., Streule W., Zengerle R., Koltay P., IMTEK, University of Freiburg, DE

Simulation of micro pumps is complicated by the interaction of various physical domains. The fluid structure interaction (FSI) essentially determines the dynamics of micro pumps and therefore has to be taken into account. Mesh based [...]

Fabrication of Microfluidic Cells with Liquid Core Waveguide and 1,1’-Oxalydiimidazole Chemiluminescence Detection

Lee J-H., Tartaglia A., Schlautman M.A., Carraway E.R., Clemson University, US

We have developed simple and inexpensive microfluidic cells (inner diameter: 100 _m) based on the principles of liquid core waveguide (LCW) and rapid 1, 1’-oxalyldiimidazole derivative chemiluminescence (ODI-CL) reactions. The microfluidic cells devised in this [...]

Sample Concentration by Asymmetry EOF flow in Micro/Nano Channels with O2/H2O Plasma Treated Channel Surfaces

Wu R-Q, Tseng F-G, Yang C-S, Cheing C-C, National Tsing Hua University, TW

In this study, we propose a new technique to concentrate sample effectively, which employs different surface treatment on the top and bottom of micro/nano channels. This treatment carries out different zeta-potentials on the opposite walls [...]

Compact Model of a Laminar Micro Mixer

Cupelli C., Koltay P., Zengerle R., Santer M., University of Freiburg, DE

In this paper we discuss a novel approach towards a system-level description for microreactors. In particular, a compact model for laminar micromixers for fluids with different viscosities is presented. We show how the well known [...]

Computational Modeling and Simulation of Microfluidic Biochips for Parallel Biomolecular Synthesis

Kan H-C, National Center for High-performance Computing, TW

In this study, a novel microfluidics based biochip has been developed by the aid of analytical modeling and numerical simulation efforts for the purpose of massively parallel oligonucleotude-DNA (oDNA) syntheses. The microfluidic biochip consists of [...]

Valving in Microchannels via Electrodeposition on Solid Electrolytes

Kozicki M.N., Maroufkhani P., Mitkova M., Arizona State University, US

We have recently developed a reliable and inexpensive way to electrically regulate flow through microchannels via a structure that can be made using readily available microfabrication techniques. We use an electrical signal to stimulate silver [...]

Characteristics of Bacterial Pumps in Microfluidic Systems

Kim M-J, Breuer K.S., Brown University, US

In this paper we show that (i) the flow-deposition of bacteria can successfully create a live bacterial carpet to generate local fluid motion inside a microfabricated system; (ii), that the carpet-activated microfluidic system can be [...]

Multiobjective Evolution Strategies for Optimization of Microfluidic Mixing

Mautner T., Consultant, Technology Development, US

microfluidics, lattice Boltzmann, opimization, biosensor Summary: An investigation has been performed to determine the effect of various surface temperature distributions on the mixing of a binary fluid. Lattice Boltzmann simulations were conducted on a binary [...]

Modeling, Analysis and Design of Centrifugal Force Driven Transient Filling Flow into Rectangular Microchannel

Kim D.S., Kwon T.H., Pohang University of Science and Technology, KR

In this paper, we first present successful modeling and analysis results of a centrifugal force driven transient filling flow into a rectangular microchannel. Two types of exact and pseudo-static approximate solutions were derived for the [...]

Design, Modelling and Simulation of a PZN-PT Actuated Micropump

Malleo D., Haas C., Kraft M., University of Southampton, Microelectronics Group, UK

We present an optimization methodology for the design of a self-priming piezoelectrically actuated pump made of a borosilicate glass bonded to silicon. New findings in the design optimization of the piezo-actuated membrane are presented: it [...]