Berthier J., Dalle P., Rivera F., Renaudot R., Morales S., Benhamou P-Y., Caillat P.
CEA-LETI, FR
Keywords: encapsulation, FFD, flow regime, live cells
Flow focusing devices (FFD) have emerged as a powerful tool for cell encapsulation and formation of micro-emulsions [1,2]. In the frame of live cell encapsulation, a micro-FFD using alginate solutions for the capsule and powered by highly controllable pressure pumps has been developed [3,4]. This work deals with the different aspects of the problem: the rheology of alginates, the flow regimes and flow charts, the influence of the different parameters and a scaling analysis. Experimental observations of capsules produced in the microsystem are finally shown.
Journal: TechConnect Briefs
Volume: 2, Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational
Published: June 13, 2011
Pages: 458 - 461
Industry sectors: Advanced Materials & Manufacturing | Sensors, MEMS, Electronics
Topic: Micro & Bio Fluidics, Lab-on-Chip
ISBN: 978-1-4398-7139-3