Simultaneous Topography and RECognition Mapping with PicoTREC™: A Powerful New Technology That Can Be Used To Map Nanometer-Scale Molecular Binding Sites On A Variety Of Surfaces

Ebner A.; Gruber H.; Hinterdorfer P.; Johnson W.T.; Kada G.; Kienberger F.; Lindsay S.; Stroh C.; Wang H.

Simultaneous Topography and RECognition Mapping with PicoTREC™: A Powerful New Technology That Can Be Used To Map Nanometer-Scale Molecular Binding Sites On A Variety Of Surfaces

Johnson W.T., Kada G., Stroh C., Gruber H., Wang H., Kienberger F., Ebner A., Lindsay S., Hinterdorfer P.
Molecular Imaging, Corp., US

Keywords: AFM, imaging, recognition, single molecule, SPM

PicoTRECTM is a new Topography and RECognition imaging solution that requires no fluorescence, radioactivity, enzyme-linked detection schemes or other extraneous labels. It combines real-time detection of molecular recognition events and single-molecule sensitivity with the imaging capability of AFM/SPM. PicoTREC allows a researcher to quickly determine where specific, single molecule binding interactions occur on a sample and resolves them from surface topography information.

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Journal: TechConnect Briefs
Volume: 2, Technical Proceedings of the 2005 NSTI Nanotechnology Conference and Trade Show, Volume 2
Published: May 8, 2005
Pages: 679 - 682
Industry sector: Advanced Materials & Manufacturing
Topic: Materials Characterization & Imaging
ISBN: 0-9767985-1-4