Lee B.K., Kwon D.Y., Kwon J.S., Park J.H., Kwon D.Y., Kwon J.S., Kim J.H., Kim M.S., Oh S.H., Kim J.H., Kim M.S.
Ajou University, KR
Keywords: diblock copolymer, in vivo, phase transition, thermogelling materials
To investigate thermogelling behavior, in this study, methoxy polyethylene glycol-b-[poly(ε-caprolactone)-ran-poly(6-chloride-ε-caprolactone) (PCL-ran-PfCL)] (PCL-Cl) diblock copolymers were designed such that the PfCL content in the PCL segment was varied. The PCL-Cl diblock copolymers were derivatized by introducing a pendant amine group at the PfCL segment (PCL-NH2). We confirmed that that PCL-NH2 diblock copolymer solution may potentially be used as thermogelling materials into the body in a minimally invasive manner.
Journal: TechConnect Briefs
Volume: 3, Biotech, Biomaterials and Biomedical: TechConnect Briefs 2015
Published: June 14, 2015
Pages: 327 - 330
Industry sectors: Advanced Materials & Manufacturing | Personal & Home Care, Food & Agriculture
Topic: Personal & Home Care, Food & Agriculture
ISBN: 978-1-4987-4729-5