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Improvement of Polycaprolactone Nanofibers Topographies: Testing the Influence in Osteoblastic Proliferation

Martins A., Cunha J., Macedo F., Reis R.L., Neves N.M., University of Minho, PT
The nanofiber technology of present interest focuses on the electrospinning technique, which conveniently allows the preparation of fibrous materials with very fine diameters ranging from submicron to several nanometers. With the ability to form nanofibrous [...]

DNA/Cellulose hybrid nanomaterials

Mangalam A., Simonsen J., Benight A.S., Oregon State University, US
One potential advantage of nanotechnology is the ability to engineer bottom-up hierarchical assembly of nanoparticles into functional macroscale materials and devices. The most promising mechanism for accomplishing this is self-assembly. In this project, an advanced [...]

3D Microfabricated Bioreactors

Xia C.-G., Fang N., University of Illinois at Urbana-Champaign, US
We present here an innovative three dimensional microfabrication technology that will serve as a vehicle to enable vascularized bioreactors for in vitro tissue culture. The core of our microfabrication technology is a high-resolution projection micro [...]

Transport of Multiple Enzymes through Semipermeable Membrane and Effect of Surfactants

Trigo C., Leung S.W., Bhushan A., Daniels C.K., Lai J.C.K., Idaho State University, College of Engineering, US
Surfactants are known to influence functions of many proteins in membranes, cells and tissues. Because most studies to elucidate the effects of surfactants on membrane-bound proteins and cells employed heterogeneous or complex systems, it is [...]

Nano-Structured Biodegradable Ceramics for the Treatment of Osteoporosis

Balasundaram G., Webster T.J., Purdue University, US
There are a number of applications requiring bone-building agents. For example, osteoporosis is a disease resulting in weak bone. However, no current effective prevention and treatment methods exist for osteoporosis. For these reasons, in this [...]

Study of Bioactive Films Using Natural Macromolecules

Ferreira M., Zucolotto V., Mulato M., Oliveira Jr O.N., FFCLRP-USP, BR
The control of interactions between living cells and modified surfaces is important for tissue engineering and may assist in the fabrication of bioactive coatings. Here we investigated the attachment of fibroblasts cells on bio-surfaces fabricated [...]

Stem cell differentiation on nano-structured carbon surfaces

Ercan B., Price R., Webster T.J., Purdue University, US
The research is based on the differentiation of stem cells on carbonnanofibers.

Multicomponent Coatings Improve the Biocompatibility of Load-bearing Implants

Chissov V.I., Reshetov I.V., Frank G.A., Levashov E.A., Shtansky D.V., Filushin M.M., Efremov G.D., Sukharev S.S., P.A.Hertzen Moscow Research Oncological Institute, RU
New implants are studied in vivo under the conditions, when the replaced defect is located on the bone, which accomplishes motions with the large amplitude and with the large load.Three types of implants were placed [...]

Increased Osteoblast Adhesion on Nano-rough Anodized Titanium and CoCrMo

Yao C., Slamovicha E.B., Webster T.J., Purdue University, US
Titanium and cobalt-based alloys are two main groups of metallic materials widely used in orthopedic applications. One approach to improve biological properties of current titanium and CoCrMo implant is to mimic the nanostructures of natural [...]

Qualitative Evaluation of the Response of Human Osteoblast Cells to Nanotopography Surfaces Based on Carbon Nanotubes

Firkowska I., Giannona S., Rojas-Chapana J., Giersig M., Center of Advanced European Studies and Research, DE
The organization of cells within an extracellular matrix is critical to promote appropriate cellular interactions and tissue function in vivo. The ability to design and create a nano-patterning on surfaces provides new capabilities for tissue [...]

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