Papers – Page 631 – TechConnect Briefs

Multiwalled Carbon Nanotube-Doxorubicin Supramolecular Complexes for Cancer Therapeutics

Ali-Boucetta H., Al-Jamal K.T., Kostarelos K., The School of Pharmacy, University of London, UK

The field of drug delivery is being revolutionised by the discovery of novel nanomaterials such as carbon nanotubes (CNTs) capable of traversing the plasma membrane and promoting the cellular uptake of small molecules and macromolecules [...]

5-aminolevulinic Acid Conjugated Gold Nanoparticles for Cancer Treatment

Khaing Oo M.K., Yang X., Wang H., Du H., Stevens Institute of Technology, US

To improve 5- aminolevulinic acid’s (5-ALA) selective retention in tumor cells and efficient damage tumor cells in photodynamic therapy (PDT), biocompatible gold (Au) nanoparticles were proposed as the carrier to selectively deliver 5-ALA into tumor-like [...]

Strategies for enhanced brain tumor accumulation of magnetic nanoparticles for potential drug delivery

Chertok B., David A.E., Yang V.C., University of Michigan, US

The purpose of this study was to elucidate strategies to enhance magnetically mediated accumulation of iron-oxide-based nanoparticles in brain tumors for potential localized delivery of chemotherapeutic agents. In particular, we evaluated administration of the nanoparticles [...]

Gold Nano-Probes as Targeted CT Contrast Agents for In-vivo cancer Imaging

Popovtzer A., Popovtzer R., Agrawal A., Shlomi M., Popovtzer A., Popovtzer R., Balter J., Carey T.E., Kopelman R., University of Michigan, US

This research describes a new class of immuno-targeted and cancer specific CT contrast agents, which enable CT imaging of cancer at cellular and molecular resolution. The method is based on the development of gold nano-probes [...]

Nanomedicine: Engineering of a Tri-Imageable Nanoparticle for Cancer Diagnostics

Bumb A., Dobson PJ., Fugger L., Choyke P., Brechbiel MW., National Cancer Institute/University of Oxford, US

We have created a potential targeted drug delivery platform with three imaging reporters by coupling the magnetic properties of USPIOs with near infrared fluorescence of Cy5.5 and gamma emissions of Indium-111 that is chelated to [...]

Why Does One Nano Lab Cost More Than Another?

Wilson W., Gregg A., Wilson Architects, US

Construction costs of nano labs reflect the differential between the required performance criteria and the in situ conditions. Nano retrofits in existing buildings range from $300 to $1000 NSF, depending on the isolation required. New [...]

Partnering in Nanotechnology Ventures: Critical Decision Factors

Woolley J.L., Santa Clara University, US

Business executives are often faced with the decision of whether to optimize the firm’s performance by partnering with another company or exploring growth alone. Although nanotechnology firms are no exception, the high level of tacit [...]

Nanotechnology in Pharmaceutical Education In USA

Pathak Y.V., Koomer A., Sullivan University College of Pharmacy, US

Nanotechnology is on its way to make a big impact in Biotech, Pharmaceutical and Medical diagnostics sciences. A dynamic collaboration is observed within the Researchers, Government, Pharmaceutical - Biomedical companies and educational institutions all over [...]

Designing the new engineer and scientist

Wauters J., De Wachter J., Flanders Investment and Trade - Consulate General of Belgium, US

Bio-nano science and technology is reaching a high level of technical expertise and knowledge. It opens up completely new ways of design, production and manufacturing. It has the capacity to impact the whole industry, the [...]

MEMS and NEMS research for education

Husak M., Jakovenko J., Czech Technical University in Prague, CZ

The paper describes methods of active involvement of students in research work and application of research work results in educational process. Individual tasks are parts of solutions of large research projects. Individual work contributes to [...]