Papers – Page 618 – TechConnect Briefs

Magnetically associated carbon nanotubes with mammalian cells: flow cytometry characterization and applications

Cai D., Blair D., Dufort F.J., Gumina M.R., Huang Z., Hong G., Kempa K., Ren Z.F., Chiles T.C., Boston College, US

Magnetic CNT can be driven into cells because it has an embedded Ni nanoparticle in its tip. We show herein that CNT-cell complexes are formed in the presence of a magnetic field. The complexes were [...]

The different biological activity between the colloidal silver nanoparticle and the plasma silver nanoparticle in various cell types

Kim S-G, Hallym University, KR

Purpose: The objective of this study was to exam any difference after treatment of nanoparticle in cellular proliferation and gene expression in various cell types. Particularly, it was compared between the colloidal silver nanoparticle and [...]

Low molecular weight heparin-vectorized _-cyclodextrin nanostructures

Vismara E., Pizzolato D., Bertini S., Torri G., Valerio A., Politecnico, IT

We set up different synthetic approaches to afford new different nanostructures cyclodextrin – low molecular weigh heparin (LMWH) characterized by covalent bonds (amine or amide) between -cyclodextrin and LMWH in different positions of the heparin [...]

Temperature Sensitive Liposomes for Local Drug delivery Using Focused Ultrasound

Larabi M., Mackanos M., Shinde R., Contag C., Guccione S., Stanford University, US

Local delivery of therapeutic drugs will increase drug concentration at the site of treatment for maximum efficacy, and reduce systemic drug exposure. The encouraging results obtain in first phase of the clinical study of doxorubicin [...]

Myelin-mimetic lipid multilayers

Iyer S., Dattelbaum A., Majewski J., Shreve A., Los Alamos National Laboratory, US

The myelin sheath is among nature’s most fascinating nanoscale assemblies. In spite of its critical role in physiology, several questions on the structure-function relationship of myelin and its components remain unanswered. This is chiefly due [...]

Quantum dot (Qdot) labeling of gene expression analysis and single molecule imaging in neurons

Jeromin A., Riley Z., Byrnes E., Parry S., Smith S., Dee N., Jones A., Allen Institute for Brain Science, US

The Allen Brain Atlas1 is the first large scale atlas of gene expression in the mouse brain, using chromogenic in situ hybridization (cISH) of over 20,000 genes.Qdots have excellent potential for muliplex imaging of gene [...]

CNT and Organic FETs Based Two-Way Transducing of the Neurosignals

Sklyar R., Independent researcher, UA

A superconducting field-effect transistor (SuFET) based neurotransducer (sensor) with carbon nanotubes (CNT) or pickup coil kind of input circuit for the nerve and neuron impulse has been designed. Electronic or ionic currents in conductors or [...]

Advances in Automated 3D cortex image data acquisition

Lich B., Greiser J., Faber P., Knott G., FEI Company, NL

The study of the 3D architecture of cortex requires the creation of image datasets with sufficient detail in all directions. The detail level required to produce meaningful data requires imaging quality that allows identification of [...]

Evaluation For The Current Management of Pompe Disease

Khan U.A., University of Manchester, UK

Pompe disease in an autosomal recessive inherited condition characterised by deficiency of the enzyme acid -glucosidase. This causes accumulation of glycogen in muscles, significantly in the heart. The affect is a progressive muscle dysfunction, leading [...]

Evolutionary selection of bone mineral hydroxyapatite binding peptide using landscape phage library

Modali S., Abbineni G., Jayanna P., Petrenko V., Mao C., University of Oklahoma, US

Hydroxyapatite [(Ca5(PO4)3OH)2] is a biomineral which is associated with bone proteins to form mineralized extracellular matrix in a mature bone. Using two landscape phage libraries, in which random octa-peptides and nona-peptides are displayed on all [...]