Bioluminescent Model for the Quantification of Photothermal Ablative Breast Cancer Therapy Mediated by Near-Infrared Nanoparticles

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Multifunctional nanoparticles hold promise for enabling non-invasive image guided cancer therapy such as photothermal therapy. Human breast tumor models in which response to image guided therapy can quickly and non-invasively be determined are needed to facilitate translation and application of these technologies. We have developed a murine model capable of investigating the effects of photothermal ablative therapy and the fate of nanomaterials following photothermal therapy. The findings suggest the potential for a new paradigm for non-invasive breast cancer therapy.

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Journal: TechConnect Briefs
Volume: 3, Nanotechnology 2010: Bio Sensors, Instruments, Medical, Environment and Energy
Published: June 21, 2010
Pages: 386 - 389
Industry sector: Medical & Biotech
Topics: Biomaterials, Cancer Nanotechnology
ISBN: 978-1-4398-3415-2