surface enhanced Raman scattering

Plasmonic nanodome array fabricated on plastic as a dual-mode surface plasmon resonance and surface-enhanced Raman scattering sensor

Choi C-J, Semancik S., National Institute of Standards and Technology, US

Label-free optical sensors have recently emerged as a highly sensitive approach for detecting a broad range of chemical and biological analytes that include illicit drug compounds, explosives, proteins, viruses, and bacteria.To best meet such diverse [...]

SERS Gold Nanoparticles for Cancer Surface Marker Detection

Nguyen C.T., Nguyen J., Nguyen C.T., Nguyen J., Rutledge S., Wang C., Walker G.C., University of Toronto, CA

Surface Enhanced Raman Scattering (SERS) gold nanoparticles may provide novel optical tags for cellular analysis. Currently, cell markers are mostly assessed by fluorescence labeling using flow cytometry. However, fluorescence dyes are usually limited to 4-5 [...]

5-aminolevulinic Acid Conjugated Gold Nanoparticles for Cancer Treatment

Khaing Oo M.K., Yang X., Wang H., Du H., Stevens Institute of Technology, US

To improve 5- aminolevulinic acid’s (5-ALA) selective retention in tumor cells and efficient damage tumor cells in photodynamic therapy (PDT), biocompatible gold (Au) nanoparticles were proposed as the carrier to selectively deliver 5-ALA into tumor-like [...]

Fabrication of Bowtie Nano-Gap Structures by Electron Beam Lithography

Murali R., Walters E., Zaman F., Tabor C., Huang W., El-Sayed M., Meindl J.D., Georgia Tech, US

Metallic nano-particle pairs in close proximity to one another display surface-enhanced raman scattering (SERS). Single-molecule detection has been predicted to be possible thanks to SERS. The SERS enhancement is due an induced localized electric field [...]