spr – TechConnect Briefs

Robust thin spin-coated silver films with polymer thin layers for SPR image sensor applications

Son J.-H., Cho Y-J, Lee M.H., Sungkyunkwan University, KR

We fabricated thin silver films with thicknesses of 20 nm, 40 nm, and 60 nm on a prism using a spin coating method for SPR image sensor module applications. An aqueous silver ionic complex solution [...]

Micrwave based microfluidic sensor

Tanbakuchi H., Bynum M., Brennen R., Whitener M., Agilent Technologies, US

SPR ( surface Plasmon Resonance) is an non destructive sensor capable of measuring the changes in refractive index above the gold surface (~300 nm) .The advantage of the SPR is in its capability of looking [...]

Au Nanoparticle Coupled- Surface Plasmon Resonance Immuno-sensor for Sensitivity Enhancement

Kim H-S, Kim J.H., Kim H-S, Kim J.H., Ko S-H., Cho Y-J, Kim H-S, Kim J.H., Ajou University, KR

In order to overcome the sensitivity limitation of SPR, nanoparticle-coupled SPR biosensors have explored since nanoparticles may significantly enhance the sensitivity by 1-2 orders of magnitude. Although the nanoparticle conjugated method contributes to the enhancement [...]

Au Nanoparticle Coupled- Surface Plasmon Resonance Chemical Sensor for Sensitivity Enhancement

Kim H-S, Kim J.H., Choi S-W, Kim H-S, Kim J.H., Cho Y-J, Choi S-W, Ajou University, KR

In order to overcome the sensitivity limitation of SPR, nanoparticle-coupled SPR biosensors have explored with tremendous interests since nanoparticles may significantly enhance the sensitivity by 1-2 orders of magnitude. M. J. Natan et al. reported [...]

Optimizing antibody microarrays for high resolution SPR microscopy

Kim G., Nishimoto A., Cong S., Johnson E., Guan H.W., Petcavish B., Lasky S., Hood L., Campbell C.T., Lumera Corporation, US

A high resolution surface plasmon resonance (SPR) microscopy technique based on the combination of Lumera’s polymer and proprietary optic technologies offers parallel high-throughput analysis of biomolecular binding kinetics on high-density antibody microarrays ( > 1,500 [...]

A Demonstration of High-throughput Immunoassay and Small Molecule Binding on Protein Microarrays with SPR Microscopy

Kim G., Jiang L., Rathod P.K., Campbell C.T., Nishimoto A., Casasanta V., University of Washington, US

The use of Surface Plasmon Resonance (SPR) for the detection of biomolecular binding events at the nanometer scale is of great utility when expanded into microarray density formats. Protein microarray analysis is particularly well suited [...]