single particle ICP-MS – TechConnect Briefs

Using single particle ICP-MS as a tool for understanding metallonanoparticles transformation during nanotoxicity assays

Johnson M.E., Hanna S.K., Petersen E.J., Nelson B.C., Yu L.L., National Institute of Standards and Technology, US

The work presented will establish a method for employing SP-ICP-MS toward the characterization of ENPs following their exposure to a model organism, C. elegans. Sample preparation, SP-ICP-MS analysis, data processing, particulate transport efficiency evaluation, and [...]

Use of Single Particle Inductively Coupled Plasma Mass Spectrometry to Characterize a New Silver Nanoparticle Reference Material

Murphy K.E., Liu J., Guthrie W.F., Gorham J.M., Bonevich J.E., Allen A.J., Winchester M.R., Hackley V.A., MacCuspie R.I., National Institute of Standards and Technology, US

In this study we use a conventional inductively coupled plasma mass spectrometer operated in single particle mode (spICP-MS) to simultaneously characterize the size distribution and dissolved silver fraction of a new candidate silver nanoparticle reference [...]

Characterization of Core-Shell nanoparticles using Field-Flow Fractionation and Single-Particle ICP-MS

Tadjiki Soheyl, Montano Manuel, Ranville James, Beckett Ron, Postnova Analytics, US

A methodology has been developed to measure mass, size and density of the core and the shell of a core-shell nanoparticle for the first time. The FFF-based methodology allows for the measurement of the mass [...]

Optimizing Instrument Operation and Data Processing for Single Particle Inductively Coupled Plasma Mass Spectrometry Measurement of Gold Nanoparticles

Liu J., Murphy K.E., MacCuspie R.I., Winchester M.R., National Institute of Standards and Technology, US

In recent years, inductively coupled plasma mass spectrometry (ICP-MS) operated in time-resolved analysis (TRA) mode has merged as a promising analytical tool capable of both sizing and counting metal containing nanoparticles in aqueous suspensions. In [...]